Description

Dalacin (clindamycin) Vaginal Cream 2% 20 g

Ingredients

Active ingredient: Clindamycin phosphate 2% w/w. Other ingredients: benzyl alcohol, sorbitan monostearate, polysorbate 60, propylene glycol, and purified water.

Dosage

Adults: Insert one applicatorful (approximately 5 g of cream) intravaginally at bedtime for 7 consecutive days.

Indications

Dalacin Vaginal Cream is indicated for the treatment of bacterial vaginosis (BV) in non-pregnant women.

Contraindications

Do not use Dalacin Vaginal Cream if you have a history of inflammatory bowel disease or antibiotic-associated colitis.

Directions

Wash hands before and after use. Insert the cream deeply into the vagina using the applicator provided. Avoid sexual intercourse during treatment.

Scientific Evidence

Clindamycin, the active ingredient in Dalacin Vaginal Cream, is a lincosamide antibiotic that works by inhibiting bacterial protein synthesis. Studies have shown its efficacy in treating BV by reducing the overgrowth of harmful bacteria in the vagina.

Additional Information

It is important to complete the full course of treatment as prescribed, even if symptoms improve before the end of the treatment period. Consult a healthcare provider if symptoms persist or worsen after treatment.

Pharmacological Effects: Clindamycin exerts its antibacterial effects by binding to the 50S subunit of the bacterial ribosome, thus inhibiting protein synthesis. This action leads to the suppression of bacterial growth and eventual eradication of the infection.

Clinical Trials: Clinical trials have demonstrated the effectiveness of clindamycin in the treatment of BV, with significant improvements in symptoms such as vaginal discharge, odor, and itching. Comparative studies have shown clindamycin to be equally effective or superior to other antibiotics commonly used for BV treatment.