Description
Decriz (Eplerenone) Coated Tablets 25 mg. №30
Ingredients
Active ingredient: Eplerenone 25 mg.
Other ingredients: lactose monohydrate, corn starch, hypromellose, magnesium stearate, titanium dioxide, polyethylene glycol.
Mechanism of Action
Pharmacological Properties: Eplerenone is a selective aldosterone blocker that works by blocking the effects of aldosterone, a hormone that can raise blood pressure. By blocking aldosterone, eplerenone helps to lower blood pressure and reduce the strain on the heart.
Indications for Use
Indications: Decriz (Eplerenone) tablets are indicated for the treatment of hypertension to lower blood pressure.
Contraindications
Contraindications:
- Do not use Decriz tablets if you are allergic to eplerenone or any other ingredients in the product.
- Avoid if you have severe kidney problems.
- Avoid use if pregnant or breastfeeding.
Side Effects
Common side effects may include dizziness, headache, or hyperkalemia. Consult your healthcare provider if you experience any adverse reactions.
Usage Instructions
Dosage: The usual starting dose is 25 mg once daily. Dosage may be increased to a maximum of 50 mg once daily based on blood pressure response.
Administration: Take Decriz tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water. It can be taken with or without food.
Benefits Compared to Analogues
Decriz tablets offer the benefit of selective aldosterone blockade with proven efficacy in lowering blood pressure and improving cardiovascular outcomes compared to other antihypertensive agents.
Suitable Patient Groups
Decriz tablets are suitable for adult patients with hypertension. Special caution should be exercised when prescribing to elderly patients or individuals with hepatic impairment. Use in children should be determined by a healthcare provider.
Storage and Packaging
Storage: Store Decriz tablets in a cool, dry place away from direct sunlight. Keep out of reach of children.
Shelf Life: Check the expiration date on the packaging. Do not use after the expiration date.
Packaging: Decriz tablets are available in a pack of 30 coated tablets.
Clinical Evidence and Proven Effectiveness
Clinical Studies: Studies have shown that eplerenone is effective in reducing blood pressure in patients with hypertension. Research published in the Journal of Clinical Hypertension demonstrated the efficacy of eplerenone in improving cardiovascular outcomes. Clinical trials have also shown that eplerenone is well-tolerated and effective in the treatment of hypertension. A study published in the American Journal of Hypertension found that eplerenone significantly reduced blood pressure compared to a placebo, with a good safety profile.
Additional Information
Important Note: Decriz tablets may interact with other medications, so inform your doctor about all the drugs you are taking. Regular monitoring of potassium levels is recommended during treatment with eplerenone.
