Description
Decriz (Eplerenone) Coated Tablets 50 mg. №30
Ingredients
Active ingredient: Eplerenone 50 mg.
Other ingredients: lactose monohydrate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol.
Mechanism of Action
Eplerenone works as a selective aldosterone blocker, antagonizing aldosterone receptors to reduce sodium and water retention. This mechanism helps in lowering blood pressure and improving cardiac function, especially in conditions like heart failure and hypertension.
Pharmacological Properties
Eplerenone, the active component of Decriz tablets, exerts its pharmacological effects by blocking aldosterone receptors, leading to decreased sodium and water reabsorption. This action results in reduced blood pressure and improved cardiovascular function.
Indications for Use
Decriz (Eplerenone) coated tablets are indicated for the treatment of essential hypertension and heart failure following a myocardial infarction.
Contraindications
Avoid using Decriz (Eplerenone) coated tablets if you have a known allergy to eplerenone or any other components of the product. Additionally, individuals with hyperkalemia or severe renal impairment should not take this medication.
Side Effects
Common side effects of Decriz (Eplerenone) tablets may include hyperkalemia, dizziness, fatigue, and gastrointestinal disturbances. Contact your healthcare provider if you experience any persistent or severe side effects.
Usage Instructions
It is recommended to take one 50 mg tablet of Decriz (Eplerenone) orally once daily. Follow the dosage instructions provided by your healthcare provider. Swallow the tablet whole with a glass of water, with or without food.
Benefits Compared to Analogues
Eplerenone offers a more selective action compared to drugs like spironolactone, potentially leading to fewer hormonal side effects. This selectivity makes Eplerenone a preferred choice in the management of hypertension and heart failure.
Suitable Patient Groups
Elderly patients and individuals with hypertension or heart failure post-myocardial infarction may benefit from the use of Decriz (Eplerenone) tablets. However, dosage adjustments may be necessary based on individual health conditions.
Storage and Shelf Life
Store Decriz (Eplerenone) coated tablets at room temperature, away from moisture and heat. Keep the medication out of the reach of children. Check the expiration date on the packaging and do not use the tablets beyond the specified shelf life.
Packaging Description
Decriz (Eplerenone) tablets are available in a pack containing 30 coated tablets, each with a dosage strength of 50 mg. The packaging is designed to ensure the integrity and stability of the tablets until the expiration date.
Clinical Evidence and Proven Effectiveness
Eplerenone, the active ingredient in Decriz tablets, has demonstrated efficacy in reducing cardiovascular mortality and morbidity in patients with heart failure and left ventricular dysfunction post-myocardial infarction. Clinical studies, including the EMPHASIS-HF trial, have highlighted the positive outcomes associated with eplerenone use in heart failure management.
