Description
Depo-Provera (Medroxyprogesterone) Suspension 150 mg/ml. 500 mg/3.3 ml. №1
Composition
Depo-Provera contains medroxyprogesterone acetate as the active ingredient. Other ingredients include polyethylene glycol 3350, polyethylene glycol 3350 NF, and sodium chloride.
Mechanism of Action
Pharmacologically, Depo-Provera inhibits ovulation, thickens cervical mucus to impede sperm penetration, and alters the endometrium to decrease the chances of implantation, thereby ensuring its high contraceptive efficacy.
Pharmacological Properties
Depo-Provera is a progestin-only contraceptive that acts by suppressing ovulation and modifying cervical mucus and the endometrium to prevent fertilization and implantation.
Indications for Use
Depo-Provera is indicated for pregnancy prevention and serves as a highly effective contraceptive method when administered correctly and consistently.
Contraindications
Individuals with a history of thrombosis, liver disease, certain cancers, or pregnancy should avoid using Depo-Provera due to potential risks associated with these conditions.
Side Effects
Common side effects of Depo-Provera may include changes in menstrual bleeding patterns, weight gain, headaches, and breast tenderness. It is advisable to consult a healthcare provider for further guidance.
Usage Instructions
Depo-Provera should be administered as a 150 mg/ml intramuscular injection every 3 months. Each vial contains 500 mg/3.3 ml of the suspension. Adherence to the prescribed dosing schedule is crucial for optimal contraceptive effectiveness.
Benefits Compared to Analogues
Clinical studies have demonstrated that Depo-Provera exhibits a failure rate of less than 1% when used correctly, showcasing its high efficacy as a long-acting reversible contraceptive method comparable to intrauterine devices. Its ease of use and extended duration of action make it a preferred choice globally.
Suitable Patient Groups
Depo-Provera is suitable for women seeking reliable contraception, including adolescents, adults, and the elderly. However, individual patient factors should be considered when determining the appropriateness of this contraceptive method.
Storage and Shelf Life
Store Depo-Provera as per the manufacturer’s instructions, away from light and moisture, at the recommended temperature range. Check the expiration date on the packaging and do not use expired products.
Packaging Description
Depo-Provera is available in vials containing 500 mg/3.3 ml of the suspension, ensuring accurate dosing and ease of administration by healthcare professionals.
