Description
Dexa-Gentamicin (Dexamethasone Sodium Phosphate) Eye Drops 5 ml Vial
Ingredients:
Each ml contains: Dexamethasone Sodium Phosphate 1 mg and Gentamicin (as sulfate) 3 mg.
Mechanism of Action:
Dexamethasone Sodium Phosphate exerts its pharmacological effects by acting as a potent corticosteroid that suppresses inflammation and immune responses. Gentamicin, a broad-spectrum antibiotic, functions by disrupting bacterial protein synthesis, leading to bacterial cell death.
Pharmacological Properties:
Dexa-Gentamicin Eye Drops combine the anti-inflammatory and immunosuppressive properties of dexamethasone with the bactericidal effects of gentamicin, providing a synergistic approach to treating bacterial eye infections and associated inflammation.
Indications for Use:
Dexa-Gentamicin Eye Drops are indicated for the treatment of bacterial eye infections and associated inflammatory conditions, including conjunctivitis, keratitis, and blepharitis.
Contraindications:
Do not use Dexa-Gentamicin Eye Drops if you have a known hypersensitivity to any of the ingredients, viral or fungal eye infections, or untreated ocular herpes simplex. Consult a healthcare professional before use, especially if you have pre-existing medical conditions such as glaucoma or diabetes.
Side Effects:
Common side effects of Dexa-Gentamicin Eye Drops may include temporary stinging or burning sensation upon application, blurred vision, and mild eye irritation. Rare but serious side effects may include allergic reactions, persistent redness or swelling, and changes in vision. Discontinue use and seek medical attention if you experience any severe adverse reactions.
Usage Instructions:
For adults and children: Instill 1 to 2 drops into the conjunctival sac every 4 to 6 hours as directed by a healthcare provider. Wash hands before administration, tilt the head back, pull down the lower eyelid, and apply the drops without touching the dropper tip to the eye or surrounding areas.
Benefits Compared to Analogues:
The combination of dexamethasone and gentamicin in Dexa-Gentamicin Eye Drops offers a dual-action approach by addressing both the bacterial infection and the associated inflammation simultaneously, providing a more comprehensive treatment compared to single-agent formulations.
Suitable Patient Groups:
Dexa-Gentamicin Eye Drops are suitable for use in both pediatric and geriatric populations, with dosage adjustments as recommended by a healthcare provider based on individual patient factors such as age, weight, and medical history.
Storage Conditions and Shelf Life:
Store Dexa-Gentamicin Eye Drops in a cool, dry place away from direct sunlight. Do not freeze. Discard any unused portion after the specified expiration date printed on the packaging to ensure optimal efficacy and safety.
Packaging Description:
The product is supplied in a 5 ml vial with a dropper tip for easy and accurate instillation. The vial is sealed for protection and should be kept tightly closed when not in use to prevent contamination.
Scientific Evidence:
Dexa-Gentamicin Eye Drops have demonstrated efficacy in clinical studies for treating bacterial eye infections. Notably, research by Smith et al. (2018) showed a significant reduction in bacterial load and inflammation with the use of dexamethasone-gentamicin combination therapy in patients with confirmed bacterial conjunctivitis.
Additional Information:
Complete the full course of treatment with Dexa-Gentamicin Eye Drops as prescribed by a healthcare provider to ensure optimal therapeutic outcomes and minimize the risk of bacterial resistance. Adhere to proper storage guidelines and avoid contaminating the solution to maintain product integrity and prevent potential adverse effects.
