Description

Dexalgyn-inect (dexketoprofen) solution for injections 50 mg/2 ml. ampoules №5

Ingredients

Each ampoule contains 50 mg of dexketoprofen.

Dosage

The usual dose is 50 mg (1 ampoule) injected intramuscularly once daily.

Indications

Dexalgyn-inect is indicated for the treatment of moderate to severe pain. It is commonly used postoperatively or in conditions such as musculoskeletal pain.

Contraindications

Do not use Dexalgyn-inect in patients with a history of hypersensitivity to dexketoprofen or other NSAIDs. It is contraindicated in patients with active peptic ulcers or gastrointestinal bleeding.

Directions

Administer Dexalgyn-inect via deep intramuscular injection. It should not be mixed with other medications in the same syringe.

Scientific Evidence

Dexketoprofen, the active ingredient in Dexalgyn-inect, is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. It works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins which are mediators of pain and inflammation.

Studies have shown that dexketoprofen is effective in managing pain in various conditions, including postoperative pain and musculoskeletal disorders. A study by Varrassi et al. (2016) demonstrated the efficacy of dexketoprofen in providing rapid and sustained pain relief with a favorable safety profile.

Additional Information

It is important to monitor patients for signs of gastrointestinal bleeding or renal impairment while on Dexalgyn-inect therapy. The use of NSAIDs, including dexketoprofen, may increase the risk of cardiovascular events, especially with long-term use.

Patients should be advised to report any adverse reactions such as stomach pain, black stools, or edema to their healthcare provider promptly.