Description
Dexalgyn-inect (Dexketoprofen) Solution for Injections 50 mg/2 ml Ampoules №5
Composition
Each ampoule contains 50 mg of dexketoprofen.
Mechanism of Action
Dexketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), exerts its analgesic and anti-inflammatory effects by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that mediate pain and inflammation.
Pharmacological Properties
Dexketoprofen is a potent NSAID with strong analgesic, anti-inflammatory, and antipyretic properties. It acts by blocking the synthesis of prostaglandins involved in the inflammatory process.
Indications for Use
Dexalgyn-inect is indicated for the management of moderate to severe pain, commonly used postoperatively or in musculoskeletal pain conditions.
Contraindications
Avoid using Dexalgyn-inect in patients with a known history of hypersensitivity to dexketoprofen or other NSAIDs. It is contraindicated in individuals with active peptic ulcers or gastrointestinal bleeding.
Side Effects
Common side effects of Dexalgyn-inect may include gastrointestinal disturbances, renal impairment, and cardiovascular events. Patients should be monitored for signs of adverse reactions.
Usage Instructions
The typical dosage is 50 mg (1 ampoule) administered via deep intramuscular injection once daily. Do not mix Dexalgyn-inect with other medications in the same syringe.
Benefits Compared to Analogues
Dexalgyn-inect offers rapid and sustained pain relief with a favorable safety profile compared to other NSAIDs. Its potency and effectiveness make it a preferred choice for managing various types of pain.
Suitable Patient Groups
Dexalgyn-inect is suitable for adults of all age groups, including the elderly, but caution is advised in patients with a history of gastrointestinal issues or cardiovascular risk factors.
Storage and Shelf Life
Store Dexalgyn-inect in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product if expired.
Packaging Description
Dexalgyn-inect is available in packs containing 5 ampoules, each containing 50 mg of dexketoprofen in 2 ml solution for injections.
Clinical Evidence and Proven Effectiveness
Studies have shown that dexketoprofen is effective in managing pain in various conditions, including postoperative pain and musculoskeletal disorders. Research by Varrassi et al. (2016) demonstrated the efficacy of dexketoprofen in providing rapid and sustained pain relief with a favorable safety profile.
Additional Information
It is crucial to monitor patients for signs of gastrointestinal bleeding or renal impairment during Dexalgyn-inect therapy. Long-term use of NSAIDs, including dexketoprofen, may increase the risk of cardiovascular events. Patients should promptly report any adverse reactions to their healthcare provider.
