Description

Diacordin (diltiazem) 120 Retard Tablets with Prolonged Release 120 mg. №30

Ingredients

Active ingredient: Diltiazem hydrochloride 120 mg.
Other ingredients: lactose monohydrate, hypromellose, colloidal anhydrous silica, magnesium stearate.

Dosage

Recommended dosage: 1 tablet daily, swallowed whole with water, preferably in the morning.
Do not crush or chew the tablet.

Indications

Diacordin 120 Retard Tablets are indicated for the treatment of hypertension (high blood pressure) and chronic stable angina (chest pain).

Contraindications

Do not use Diacordin 120 Retard Tablets if you have a known hypersensitivity to diltiazem or any of the excipients.
Patients with sick sinus syndrome, severe bradycardia, or hypotension should also avoid this medication.

Directions

Take Diacordin 120 Retard Tablets exactly as prescribed by your healthcare provider.
Consult your doctor for any dose adjustments or changes in your treatment regimen.

Scientific Evidence

Diltiazem, the active ingredient in Diacordin 120 Retard Tablets, is a calcium channel blocker that works by relaxing blood vessels and increasing the supply of blood and oxygen to the heart. Studies have shown that diltiazem is effective in reducing blood pressure and improving symptoms of angina pectoris.

Additional Information

It is important to monitor blood pressure regularly while taking Diacordin 120 Retard Tablets to ensure optimal control.
Inform your healthcare provider about any other medications you are taking to avoid potential drug interactions.

Pharmacological Effects: Diltiazem inhibits the influx of calcium ions across cardiac and smooth muscle cells, leading to vasodilation and decreased peripheral resistance. This action results in reduced myocardial oxygen demand and improved oxygen delivery to the heart muscle.

Clinical Trials: Clinical trials have demonstrated the efficacy of diltiazem in the management of hypertension and angina. A study published in the Journal of the American College of Cardiology showed that diltiazem significantly reduced the frequency of angina attacks and improved exercise tolerance in patients with stable angina.