Description
Dicor Long (Isosorbide Dinitrate) Tablets with Prolonged Release 20 mg. №50
Composition
Active ingredient: Isosorbide dinitrate
Other ingredients: lactose monohydrate, microcrystalline cellulose, hypromellose, magnesium stearate, colloidal anhydrous silica.
Mechanism of Action
Isosorbide dinitrate is a vasodilator that works by relaxing the blood vessels, increasing oxygen and blood flow to the heart. This helps reduce the workload on the heart and relieve angina symptoms.
Pharmacological Properties
Isosorbide dinitrate acts as a nitrate vasodilator, leading to the relaxation of vascular smooth muscle. It dilates both arterial and venous blood vessels, reducing preload and afterload on the heart.
Indications for Use
Indicated for: Prevention and treatment of angina pectoris.
Contraindications
Do not use Dicor Long tablets if you:
- Are allergic to isosorbide dinitrate or any other ingredients.
- Have severe anemia.
- Are taking medications for erectile dysfunction like sildenafil.
Side Effects
Common side effects may include headache, dizziness, lightheadedness, and flushing. Serious side effects such as severe hypotension or methemoglobinemia may occur rarely.
Usage Instructions
Dosage: The usual dose is 20 mg once daily. Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.
Benefits Compared to Analogues
Dicor Long tablets offer the advantage of once-daily dosing due to their prolonged-release formulation, providing sustained anti-anginal effects and improving patient compliance compared to immediate-release formulations.
Suitable Patient Groups
Dicor Long tablets are suitable for adult patients with angina pectoris. Use in children, pregnant women, and elderly individuals should be under the supervision of a healthcare provider.
Storage Conditions and Shelf Life
Store the tablets in a cool, dry place away from direct sunlight. Keep out of reach of children. Check the expiration date on the packaging and do not use expired tablets.
Packaging Description
Dicor Long tablets are available in a package containing 50 tablets of 20 mg each. The packaging is designed to protect the tablets from environmental factors and maintain their efficacy.
Clinical Evidence and Proven Effectiveness
Pharmacological effects: Isosorbide dinitrate, in its prolonged-release form, has been clinically proven to provide sustained anti-anginal effects with once-daily dosing, improving exercise tolerance and reducing the frequency of angina attacks.
Clinical studies have shown: Prolonged-release formulations of isosorbide dinitrate, like Dicor Long tablets, are effective in managing angina symptoms and enhancing quality of life in patients with stable angina pectoris.
Additional Information
It is crucial to adhere to the prescribed dosage of Dicor Long tablets to optimize therapeutic benefits and minimize the risk of side effects. Inform your healthcare provider about all medications you are taking before initiating treatment with Dicor Long tablets.
