Description
Dicor Long (Isosorbide Dinitrate) Tablets with Prolonged Release 60 mg. №50 Vial
Composition
Dicor Long tablets contain 60 mg of Isosorbide Dinitrate as the active ingredient. Other inactive ingredients include lactose, maize starch, povidone, and magnesium stearate.
Mechanism of Action
Isosorbide Dinitrate, a vasodilator, relaxes blood vessels, thereby increasing oxygen and blood flow to the heart.
Pharmacological Properties
Studies have shown the efficacy of Isosorbide Dinitrate in improving exercise tolerance and reducing the need for sublingual nitroglycerin in patients with angina. Prolonged-release formulations like Dicor Long provide consistent nitrate levels, reducing tolerance development risks.
Indications for Use
Dicor Long is indicated for the prophylaxis and treatment of angina pectoris due to coronary artery disease.
Contraindications
The use of Dicor Long is contraindicated in patients with hypersensitivity to nitrates or any component of the formulation. It should not be used in patients with severe hypotension or hypovolemia.
Side Effects
Common side effects of Dicor Long may include headaches, dizziness, and flushing. Severe side effects such as fainting or allergic reactions should be reported to a healthcare provider immediately.
Usage Instructions
The recommended dosage of Dicor Long is determined by the healthcare provider based on the individual’s condition. The starting dose is typically 5 mg to 20 mg every 6 to 8 hours, with a maximum daily dose of 120 mg. The tablets should be taken whole with water, preferably on an empty stomach.
Benefits Compared to Analogues
Dicor Long with prolonged release provides sustained nitrate therapy, offering around-the-clock angina relief. Its consistent nitrate levels help reduce the risk of tolerance development compared to other formulations.
Suitable Patient Groups
Dicor Long is suitable for adult patients with angina pectoris. Dosage adjustments may be necessary for elderly patients based on individual health status.
Storage and Shelf Life
Dicor Long should be stored at room temperature away from moisture and heat. The shelf life of the product is as indicated on the packaging.
Packaging Description
Dicor Long is available in a vial containing 50 tablets of 60 mg each with prolonged release formulation.