Description

Difliucan (Fluconazole) Solution for Injections 2 mg/ml. 100 ml. Vial №1

Ingredients

Active ingredient: Fluconazole. Inactive ingredients may include sodium chloride, hydrochloric acid, and water for injection.

Dosage

Dosage: The usual dose is 400 mg on the first day, followed by 200-400 mg once daily. Dosage adjustments may be needed based on the patient’s condition.

Indications

Indications: Difliucan is indicated for the treatment of various fungal infections, including candidiasis, cryptococcal meningitis, and others caused by susceptible strains of fungi.

Contraindications

Contraindications: Difliucan is contraindicated in patients with known hypersensitivity to fluconazole or any of the inactive ingredients in the formulation.

Directions

Administration: Difliucan is for intravenous use only and should be administered by healthcare professionals. The solution should be visually inspected for particulate matter before administration.

Scientific Evidence

Fluconazole, the active ingredient in Difliucan, is a well-studied antifungal agent with a broad spectrum of activity against various fungal pathogens. Research studies have demonstrated the efficacy of fluconazole in the treatment of invasive fungal infections, including candidemia and invasive candidiasis.

Additional Information

Difliucan is a valuable option in the management of serious fungal infections, especially in immunocompromised patients. It is essential to monitor for potential drug interactions and adverse effects during treatment with Difliucan.

Pharmacological Effects: Fluconazole acts by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes, leading to cell membrane disruption and ultimately fungal cell death.

Clinical Trials: Clinical trials have shown fluconazole to be effective in the treatment of various fungal infections, with favorable outcomes and safety profiles compared to other antifungal agents.