Description

Difors 160 (amlodipine besilate and valsartan) Coated Tablets 5 mg/160 mg. №30

Ingredients:

Each tablet contains 5 mg of amlodipine besilate and 160 mg of valsartan.

Dosage:

The recommended dosage is one tablet per day, or as prescribed by a healthcare professional.

Indications:

Difors 160 tablets are indicated for the treatment of hypertension in patients not adequately controlled with monotherapy.

Contraindications:

Do not use Difors 160 if you are allergic to amlodipine, valsartan, or any other ingredients in the product.

Directions:

Swallow the tablet whole with a glass of water. It can be taken with or without food.

Scientific Evidence:

Studies have shown that the combination of amlodipine and valsartan in Difors 160 tablets provides a synergistic effect in lowering blood pressure. A meta-analysis published in the Journal of Hypertension concluded that the combination therapy was more effective than monotherapy in reducing both systolic and diastolic blood pressure levels.

Additional Information:

Difors 160 tablets have been well-tolerated in clinical trials, with a low incidence of adverse effects. It is important to follow the prescribed dosage and consult with a healthcare provider before starting or changing any medication regimen.

The pharmacological action of amlodipine involves the inhibition of calcium ion influx across cell membranes, leading to vasodilation and decreased peripheral vascular resistance. Valsartan works by blocking the vasoconstrictor and aldosterone-secreting effects of angiotensin II, resulting in vasodilation and decreased blood pressure.