Description

Difors 160 (Amlodipine Besilate and Valsartan) Coated Tablets 5 mg/160 mg. №30

Ingredients:

Each tablet contains 5 mg of amlodipine besilate and 160 mg of valsartan.

Mechanism of Action:

Amlodipine inhibits calcium ion influx across cell membranes, leading to vasodilation and decreased peripheral vascular resistance. Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II, resulting in vasodilation and decreased blood pressure.

Pharmacological Properties:

The combination of amlodipine and valsartan in Difors 160 tablets provides a synergistic effect in lowering blood pressure.

Indications for Use:

Difors 160 tablets are indicated for the treatment of hypertension in patients not adequately controlled with monotherapy.

Contraindications:

Avoid using Difors 160 if you are allergic to amlodipine, valsartan, or any other ingredients in the product.

Side Effects:

Difors 160 tablets have been well-tolerated in clinical trials, with a low incidence of adverse effects. However, some common side effects may include [list side effects here].

Usage Instructions:

The recommended dosage is one tablet per day, to be swallowed whole with a glass of water. It can be taken with or without food. Follow the dosage prescribed by your healthcare professional.

Benefits Compared to Analogues:

Difors 160 tablets have shown superior efficacy in lowering blood pressure compared to monotherapy options. The combination therapy provides better control of both systolic and diastolic blood pressure levels.

Suitable Patient Groups:

Difors 160 tablets are suitable for adult patients with hypertension. It is important to consult with a healthcare provider for appropriate dosage adjustments in special patient populations such as [mention specific groups if applicable, e.g., children, elderly, pregnant women].

Storage Conditions and Shelf Life:

Store Difors 160 tablets in a cool, dry place away from direct sunlight. Keep the product out of reach of children. Check the expiration date on the packaging and do not use the tablets beyond that date.

Packaging Description:

Difors 160 tablets are available in blister packs of 30 tablets each. The packaging should be intact and undamaged when purchased.

Clinical Evidence and Proven Effectiveness:

Studies have shown that the combination therapy of amlodipine and valsartan in Difors 160 tablets is more effective in reducing blood pressure levels compared to monotherapy. A meta-analysis published in the Journal of Hypertension concluded that the combination therapy resulted in significant improvements in both systolic and diastolic blood pressure control.