Description

Digoxin (digoxin) tablets 0.25 mg. №40

Ingredients

Active ingredient: Digoxin 0.25 mg per tablet.

Dosage

Dosage: The usual maintenance dose is 0.125-0.25 mg once daily. Dosage may vary based on individual patient factors. Consult a healthcare professional for personalized dosing.

Indications

Indications: Digoxin is indicated for the treatment of heart failure and atrial fibrillation. It helps to control heart rate and improve cardiac function.

Contraindications

Contraindications: Do not use Digoxin if you have ventricular fibrillation. Patients with hypersensitivity to digoxin or other ingredients in the formulation should also avoid its use.

Directions

Directions: Take Digoxin exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Digoxin, a cardiac glycoside, works by inhibiting the sodium-potassium ATPase pump, leading to increased intracellular calcium concentrations. This mechanism enhances myocardial contractility and reduces heart rate, making it a valuable medication for heart conditions.

Additional Information

Digoxin requires careful monitoring of blood levels due to its narrow therapeutic index. It is important to report any signs of toxicity, such as nausea, vomiting, or visual disturbances, to your healthcare provider promptly.

Pharmacological Effects: Digoxin’s positive inotropic effects make it effective in treating heart failure by improving cardiac output. It also exhibits negative chronotropic effects, slowing the heart rate, which can be beneficial in atrial fibrillation.

Clinical Trials: Research studies have shown that Digoxin reduces hospitalizations due to heart failure exacerbations and improves symptoms in patients with atrial fibrillation. It is considered a cornerstone therapy in managing certain cardiac conditions.