Description
Diocor 160 (Valsartan, Hydrochlorothiazide) Coated Tablets 160 mg/12.5 mg. №30
Ingredients
Each tablet contains 160 mg of valsartan and 12.5 mg of hydrochlorothiazide.
Mechanism of Action
Valsartan blocks the action of angiotensin II, a vasoconstrictor, leading to vasodilation and reduced blood pressure. Hydrochlorothiazide acts as a diuretic, promoting the excretion of sodium and water, further decreasing blood volume and pressure.
Pharmacological Properties
The combination of valsartan and hydrochlorothiazide synergistically lowers blood pressure by targeting different mechanisms: vasodilation and diuresis.
Indications for Use
Diocor 160 tablets are indicated for the treatment of hypertension. They can be used as monotherapy or in combination with other antihypertensive medications.
Contraindications
Avoid Diocor 160 if pregnant, with severe renal impairment, or allergic to any components. Consult a healthcare provider before starting treatment.
Side Effects
Common side effects may include dizziness, hypotension, electrolyte imbalances, and renal dysfunction. Monitor for adverse reactions and report any concerns promptly.
Usage Instructions
Take one tablet daily with a full glass of water, with or without food. Do not crush or chew the tablet. In case of a missed dose, take it as soon as remembered.
Benefits Compared to Analogues
Diocor 160 offers the advantage of dual therapy in a single tablet, providing enhanced efficacy in blood pressure control compared to monotherapy options.
Suitable Patient Groups
Diocor 160 is suitable for adult patients with hypertension, including elderly individuals. Use in pediatric patients requires specific evaluation and dosage adjustment.
Storage and Shelf Life
Store Diocor 160 in a cool, dry place away from sunlight. Check the expiration date on the packaging and do not use after the specified period.
Packaging Description
Each package contains 30 coated tablets of Diocor 160, with clear labeling of the active ingredients and dosage strength.
Clinical Evidence and Proven Effectiveness
Studies confirm the efficacy of valsartan and hydrochlorothiazide in reducing blood pressure. Research in the Journal of Clinical Hypertension highlights the superior outcomes of this combination therapy over monotherapy.
