Description

Diocor 160 (valsartan, hydrochlorothiazide) Coated Tablets 160 mg/12.5 mg. №90

Ingredients

Diocor 160 tablets contain 160 mg of valsartan and 12.5 mg of hydrochlorothiazide. Valsartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels, while hydrochlorothiazide is a diuretic that helps the body get rid of excess salt and water.

Dosage

The recommended dosage of Diocor 160 is one tablet once daily. It is important to follow the dosage instructions provided by your healthcare provider to ensure the best results.

Indications

Diocor 160 tablets are indicated for the treatment of hypertension to lower blood pressure. This medication may be used alone or in combination with other antihypertensive agents.

Contraindications

Do not take Diocor 160 tablets if you are allergic to any of the ingredients, if you are pregnant, or if you have severe liver or kidney disease. It is important to discuss your medical history with your doctor before starting this medication.

Directions

Take Diocor 160 tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Studies have shown that the combination of valsartan and hydrochlorothiazide in Diocor 160 tablets is effective in lowering blood pressure in patients with hypertension. According to a study published in the Journal of Clinical Hypertension, this combination therapy demonstrated superior blood pressure control compared to monotherapy with either component alone.

Additional Information

It is important to monitor your blood pressure regularly while taking Diocor 160 tablets to ensure that the medication is working effectively. If you experience any side effects or have concerns about this medication, consult your healthcare provider. Additionally, maintaining a healthy lifestyle with a balanced diet and regular exercise can complement the effects of Diocor 160 in managing hypertension.

Pharmacological Effects: Valsartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict. This relaxation of blood vessels helps lower blood pressure. Hydrochlorothiazide increases the excretion of sodium and water by the kidneys, leading to reduced blood volume and lower blood pressure.

Clinical Trials: Clinical trials have demonstrated the efficacy and safety of Diocor 160 tablets in the management of hypertension. A randomized controlled trial published in the American Journal of Hypertension showed that the combination of valsartan and hydrochlorothiazide was well-tolerated and effective in reducing blood pressure levels over a 12-week period.