Description
Diocor Solo 160 (valsartan, hydrochlorothiazide) Coated Tablets 160 mg. №30
Composition
Active Substances: Valsartan and hydrochlorothiazide.
Other Ingredients: lactose monohydrate, microcrystalline cellulose, crospovidone, colloidal anhydrous silica, magnesium stearate, hypromellose, macrogol 8000, titanium dioxide (E171).
Mechanism of Action
Diocor Solo 160 combines valsartan and hydrochlorothiazide to effectively lower blood pressure in patients with hypertension. Valsartan blocks the action of angiotensin II, a vasoconstrictor, while hydrochlorothiazide promotes diuresis by eliminating excess salt and water.
Pharmacological Properties
The pharmacological properties of Diocor Solo 160 stem from the synergistic effects of valsartan and hydrochlorothiazide, leading to improved blood pressure control and cardiovascular outcomes in hypertensive patients.
Indications for Use
Diocor Solo 160 is indicated for the treatment of essential hypertension in adults.
Contraindications
Do not use Diocor Solo 160 if you:
- Are allergic to any of the ingredients
- Are pregnant or breastfeeding
- Have severe liver or kidney problems
Side Effects
Common side effects of Diocor Solo 160 may include dizziness, hypotension, electrolyte imbalances, and renal dysfunction. Consult a healthcare provider if these side effects persist or worsen.
Usage Instructions
Recommended Dosage: One tablet once daily. Swallow the tablet whole with a glass of water, with or without food. Follow the prescription provided by your healthcare provider and do not exceed the recommended dose.
Benefits Compared to Analogues
Diocor Solo 160 offers the advantage of dual therapy with valsartan and hydrochlorothiazide, providing superior blood pressure control compared to monotherapy with either drug alone. The combination therapy enhances efficacy and minimizes adverse effects.
Suitable Patient Groups
Diocor Solo 160 is suitable for adult patients with essential hypertension. Dosage adjustments may be necessary for elderly individuals or those with renal impairment. Consult a healthcare provider for personalized recommendations.
Storage Conditions and Shelf Life
Store Diocor Solo 160 at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Check the expiration date on the packaging and do not use expired tablets.
Packaging Description
Diocor Solo 160 is available in blister packs containing 30 coated tablets of 160 mg each. The packaging is designed to protect the tablets from environmental factors and maintain their stability.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the efficacy of Diocor Solo 160 in lowering blood pressure and improving cardiovascular outcomes in hypertensive patients. The combination of valsartan and hydrochlorothiazide has shown superior efficacy compared to monotherapy, with a favorable safety profile.
One study published in the American Journal of Hypertension highlighted the enhanced blood pressure-lowering effects of the combination therapy, emphasizing its role in managing hypertension effectively.
Regular monitoring of blood pressure levels is essential during treatment with Diocor Solo 160 to assess the response to therapy and adjust dosages as needed. Consult a healthcare provider promptly in case of any adverse reactions or concerns.
