Description

Diocor Solo 80 (valsartan, hydrochlorothiazide) Coated Tablets 80 mg. №30

Ingredients

Active ingredients: Valsartan 80 mg, Hydrochlorothiazide 12.5 mg. Inactive ingredients: lactose monohydrate, microcrystalline cellulose, crospovidone, colloidal anhydrous silica, magnesium stearate, hypromellose, titanium dioxide (E171), macrogol 400, iron oxide yellow (E172).

Dosage

Recommended dosage: 1 tablet once daily. It is important to follow the instructions provided by your healthcare provider.

Indications

Diocor Solo 80 is indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled on monotherapy.

Contraindications

Do not use Diocor Solo 80 if: you are allergic to any of the ingredients, you are pregnant, you have severe liver or kidney problems, you have diabetes, or you are taking aliskiren.

Directions

Take Diocor Solo 80 exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water. It can be taken with or without food.

Scientific Evidence

Studies have shown that the combination of valsartan and hydrochlorothiazide in Diocor Solo 80 is effective in lowering blood pressure. A study published in the Journal of Clinical Hypertension demonstrated that this combination therapy resulted in a significant reduction in both systolic and diastolic blood pressure compared to placebo.

Additional Information

It is important to monitor your blood pressure regularly while taking Diocor Solo 80 and report any significant changes to your healthcare provider. This medication may cause dizziness, so avoid driving or operating machinery until you know how it affects you.

Pharmacological Effects: Valsartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to tighten. This helps to relax the blood vessels, which lowers blood pressure. Hydrochlorothiazide is a diuretic that helps the body get rid of excess salt and water, also reducing blood pressure.

Clinical Trials: In a randomized controlled trial involving patients with hypertension, the combination of valsartan and hydrochlorothiazide was found to be more effective in reducing blood pressure compared to valsartan alone. The study, published in the American Journal of Hypertension, concluded that the combination therapy was well-tolerated and provided significant blood pressure control.