Description
Diroton (Lisinopril) Tablets 20 mg. №28
Ingredients
Active Ingredient: Lisinopril
Other ingredients: Microcrystalline cellulose, lactose, magnesium stearate, colloidal anhydrous silica.
Mechanism of Action
Lisinopril, an ACE inhibitor, acts by relaxing blood vessels, thereby reducing cardiac workload and enhancing blood circulation.
Pharmacological Properties
Lisinopril exerts its effects by inhibiting the angiotensin-converting enzyme, leading to vasodilation and decreased aldosterone secretion.
Indications for Use
Indicated for: Hypertension, heart failure, and post-myocardial infarction.
Contraindications
Do not use if: Allergic to lisinopril, history of angioedema, pregnancy, or breastfeeding.
Side Effects
Common side effects may include dizziness, cough, or headache. It is important to consult a healthcare provider if severe side effects occur.
Usage Instructions
Dosage: The recommended dose is 20 mg once daily. Patients should seek individualized dosing guidance from a healthcare professional.
Administration: Take the tablet orally with a full glass of water. It can be administered with or without food.
Benefits Compared to Analogues
Diroton has demonstrated efficacy in lowering blood pressure and enhancing cardiac function in heart failure patients, as evidenced by clinical trials.
Suitable Patient Groups
Diroton is suitable for adult patients, including the elderly, but caution is advised in specific populations such as pregnant or breastfeeding individuals.
Storage and Shelf Life
- Storage: Keep at room temperature, protecting from moisture and heat.
- Shelf Life: Check the packaging for the expiration date and do not use after that date.
Packaging Description
The product comes in a package containing 28 tablets of 20 mg each.
Clinical Evidence and Proven Effectiveness
Lisinopril, the active component in Diroton, has been extensively studied for its efficacy in managing hypertension and heart failure. Research published in the Journal of the American College of Cardiology highlighted significant reductions in cardiovascular events and mortality rates in heart failure patients treated with lisinopril compared to a placebo group.
