Description

Disol (sodium acetate trihydrate) solution for infusions 400 ml

Ingredients

Active ingredient: Each 100 ml of solution contains sodium acetate trihydrate equivalent to sodium 0.4 g.

Dosage

Dosage: The dosage is determined by the healthcare provider based on the patient’s condition and needs.

Indications

Indications: Disol solution is indicated for the treatment of metabolic acidosis.

Contraindications

Contraindications: Do not use Disol solution in patients with hypernatremia or fluid overload.

Directions

Administration: Disol solution is for intravenous use only. It should be administered by healthcare professionals.

Scientific Evidence

Scientific evidence: Studies have shown that sodium acetate solutions can effectively correct metabolic acidosis by replenishing bicarbonate levels in the body.

Additional Information

Storage: Store Disol solution at controlled room temperature. Do not freeze.
Caution: Monitor electrolyte levels regularly during treatment with Disol solution.

Pharmacological Effects: Sodium acetate acts as a systemic and urinary alkalizer. It is converted to bicarbonate in the body, which helps in correcting metabolic acidosis. This mechanism of action makes it a valuable agent in managing acid-base imbalances.

Clinical Trials: Clinical trials have demonstrated the efficacy of sodium acetate solutions in rapidly correcting acidosis in various clinical settings. A study by Kraut et al. (2013) highlighted the effectiveness of sodium acetate in improving pH and bicarbonate levels in critically ill patients with metabolic acidosis.