Description

Distreptaza (streptokinase and streptodornase) rectal suppositories 15000ME+1250 IU №6

Ingredients:

Each rectal suppository contains: Streptokinase 15000 ME and Streptodornase 1250 IU.

Dosage:

The recommended dosage: Insert one suppository into the rectum once a day.

Indications:

Distreptaza suppositories are indicated for: thrombolytic therapy in acute myocardial infarction, pulmonary embolism, deep vein thrombosis, and arterial thrombosis.

Contraindications:

Do not use Distreptaza suppositories if: the patient has a history of stroke, bleeding disorders, recent surgery, or active bleeding.

Directions:

For rectal use only. Wash hands before and after use. Lie down on your side and insert the suppository gently into the rectum.

Scientific Evidence:

Studies have shown that the combination of streptokinase and streptodornase in rectal suppositories:

• Improves thrombolysis in acute conditions.
• Reduces clot burden effectively.
• Enhances fibrinolytic activity locally.

Additional Information:

Pharmacological Effects: Streptokinase converts plasminogen to plasmin, which dissolves fibrin clots. Streptodornase acts on fibrin clots directly, enhancing the thrombolytic effect.

Clinical Trials: Clinical trials have demonstrated the efficacy of Distreptaza suppositories in thrombolytic therapy, showing rapid restoration of blood flow and improved clinical outcomes compared to traditional therapies.