Description
Divigel (estradiol) gel 0.1% 1g. №28
Ingredients
Active ingredient: Estradiol 0.1%
Other ingredients: Carbomer, ethanol, propylene glycol, purified water.
Dosage
Dosage: Apply **1g** of Divigel daily to the skin of the thigh and rub it in until dry. Rotate application sites.
Indications
Indications: Divigel is indicated for the treatment of moderate to severe vasomotor symptoms associated with menopause.
Contraindications
Contraindications: Do not use Divigel in individuals with a history of estrogen-dependent tumors, undiagnosed abnormal genital bleeding, or during pregnancy.
Directions
Directions: Clean and dry the skin before applying Divigel. Avoid applying to broken, irritated, or sunburned skin. Wash hands after application.
Scientific Evidence
Pharmacological Effects: Estradiol, the active ingredient in Divigel, is a synthetic form of estrogen that binds to estrogen receptors in the body, exerting estrogenic effects. It helps alleviate menopausal symptoms by restoring hormonal balance.
Clinical Trials: Clinical studies have demonstrated the efficacy of Divigel in reducing the frequency and severity of hot flashes and night sweats in menopausal women. Research published in the Journal of Women’s Health showed a significant improvement in menopausal symptoms with estradiol gel therapy.
Additional Information
Precautions: **Divigel** should be used at the lowest effective dose for the shortest duration. Regularly monitor for adverse effects. Inform your healthcare provider about any medical conditions or medications before using Divigel.
Storage: Store Divigel at room temperature away from heat and moisture. Keep out of reach of children.
