Description

Dofamin (Dopamine Hydrochloride) Concentrate for Infusions 5 mg/ml. 5 ml. Ampoules №10

Ingredients:

Each 5 ml ampoule contains 25 mg of dopamine hydrochloride as the active ingredient.

Dosage:

The dosage should be individualized based on the patient’s condition and response to treatment. It is typically administered by intravenous infusion.

Indications:

Dofamin is indicated for the treatment of hemodynamic imbalances in conditions such as shock, trauma, and sepsis.

Contraindications:

Do not use Dofamin in patients with pheochromocytoma, ventricular fibrillation, or hypersensitivity to dopamine or any component of the formulation.

Directions:

Administer Dofamin under the supervision of a healthcare provider experienced in the use of vasopressor agents.

Scientific Evidence:

Dopamine, the active ingredient in Dofamin, is a naturally occurring neurotransmitter that plays a crucial role in various physiological functions, including blood pressure regulation and kidney function. By acting on dopamine receptors, Dofamin helps improve cardiac output and systemic vascular resistance, making it a valuable agent in the management of hypotension and shock.

Clinical trials have demonstrated the efficacy of dopamine in improving hemodynamic parameters and outcomes in patients with distributive shock, such as septic shock. A study by De Backer et al. (2010) showed that dopamine was associated with a higher rate of blood pressure restoration compared to norepinephrine in septic shock patients.

Additional Information:

• Dofamin should be stored at controlled room temperature between 20°C to 25°C (68°F to 77°F).
• Monitor the patient closely for signs of extravasation during infusion to prevent tissue necrosis.