$18.00
Manufacturer: Germany
For local treatment of degenerative joint diseases with pain syndrome (arthrosis), inflammatory rheumatic diseases of the joints and spine, edema or inflammation of soft tissues near the joints (for example, bursitis, tendinitis, tendovaginitis, ligament and joint capsule damage), stiffness of movements in the shoulder area, low back pain, lumbago, myalgia, sports and other injuries such as bruising, muscle strain, sprains and tendons.
Description
Dolgyt 50 g. Storage:
active substance: ibuprofen;
1 g of cream contains ibuprofen 50 mg;
Dolgyt 50 g. Excipients:
medium chain triglycerides, glycerol monostearate, polyoxyethylene-30-stearate, polyoxyethylene-100-stearate, propylene glycol, sodium methyl 4-hydroxybenzoate (E 219), xanthan gum (E 415), lavender oil, olive oil .
Dolgyt 50 g. Dosage form.
Cream.
Main physical and chemical properties:
homogeneous, soft cream from white to cream color with lavender-citrus scent.
Pharmacotherapeutic group.
Topical remedies for joint and muscle pain. ATX code M02A A13.
Pharmacological properties.
Pharmacodynamics.
Dolgit® cream is a non-steroidal anti-inflammatory and analgesic for topical use in joint and muscle pain. Ibuprofen – the active substance of Dolgit® cream – has a pronounced anti-inflammatory, analgesic and moderate antipyretic effect, reduces edema caused by inflammation caused by trauma or rheumatic diseases, improves joint mobility. The pharmacological activity of the drug is due to its ability to inhibit the synthesis of prostaglandins.
When applied topically, ibuprofen is rapidly absorbed through the skin and enters the site of inflammation. Penetration to the site of action may vary depending on the degree and type of lesion, as well as the site of application and the site of action.
In articular tissues, therapeutic concentrations are maintained for several hours, while in the serum the active substance is only a small amount, so the systemic effect is almost absent.
Pharmacokinetics.
The biological transformation of ibuprofen occurs in the liver. Pharmacologically inactive metabolites are excreted by the kidneys (90%) as well as bile. Ibuprofen is 99% bound to plasma proteins. The half-life is 1.8-3.5 hours.
Clinical characteristics.
Indication.
For topical treatment of degenerative diseases of the joints with pain (arthrosis), inflammatory rheumatic diseases of the joints and spine, edema or inflammation of the soft tissues around the joints (eg, bursitis, tendinitis, tendovaginitis, ligament and joint capsule), skuto shoulder movements, low back pain, lumbago, myalgia, sports and other injuries such as bruising, muscle strain, sprains and ligaments.
Contraindication.
Dolgit® cream is contraindicated:
– in case of hypersensitivity to the active substance ibuprofen, preservative sodium methyl 4-hydroxybenzoate, propylene glycol, to any of the components of the drug or to other analgesics and antirheumatic drugs;
– when applied to open wounds, inflammatory and infectious skin diseases such as eczema, as well as mucous membranes;
– in the last trimester of pregnancy.
Interaction with other drugs and other types of interactions.
At external use of drug according to recommendations of interaction with other medicines was not observed.
The physician should be informed of concomitant treatment with other medicinal products, if any, or of recent therapy.
Features of application.
In patients with asthma, hay fever, swelling of the nasal mucosa (rhinopolyps), chronic obstructive airways disease or chronic respiratory infections (especially with symptoms of hay fever) and in patients with hypersensitivity to analgesics and antirheumatic drugs, the development of various types of pain (analgesic intolerance / analgesic asthma), local edema of the skin and mucous membranes (Quincke’s edema) or urticaria.
The use of the drug in such patients should be carried out under special conditions and under the direct supervision of a physician. Caution should be exercised in patients with hypersensitivity (allergy) to other substances that cause skin irritation, itching, urticaria.
In case of a rash on the skin, stop using the cream immediately.
The drug is not allowed to get into the eyes.
Care should be taken to ensure that children do not touch the areas of skin on which the drug has been applied. Wash your hands thoroughly after each use if they are not being treated.
If discomfort during treatment lasts longer than 3 days, you should consult a doctor.
Due to the possible occurrence of excessive photosensitivity, patients should avoid intense exposure to sunlight / UV rays when using the drug.
Propylene glycol can cause skin irritation.
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