Description

Domperidon-Stoma (domperidone) tablets 0.01g. №30

Ingredients

Active ingredient: Domperidone 0.01g per tablet.

Dosage

Adults: The usual dose is 10mg (1 tablet) taken 3 to 4 times a day before meals and at bedtime.

Indications

Domperidon-Stoma tablets are indicated for the relief of symptoms of nausea and vomiting.

Contraindications

Do not use Domperidon-Stoma tablets if you have a known hypersensitivity to domperidone or any of the excipients.

Directions

Take Domperidon-Stoma tablets orally with a glass of water. Do not crush or chew the tablets. Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Domperidone, the active ingredient in Domperidon-Stoma tablets, is a dopamine antagonist that acts on the chemoreceptor trigger zone in the brain, exerting antiemetic effects. Studies have shown that domperidone is effective in the treatment of nausea and vomiting, especially in conditions such as gastroparesis and functional dyspepsia.

Additional Information

Domperidone has been extensively studied for its efficacy and safety profile. Clinical trials have demonstrated the effectiveness of domperidone in improving symptoms of nausea and vomiting with a favorable side effect profile. It is considered a first-line treatment option for these symptoms in many clinical guidelines.

Pharmacological Effects: Domperidone works by blocking dopamine receptors in the brain and gut. This action helps to increase the motility of the stomach and intestines, reducing the symptoms of nausea and vomiting.

Clinical Trials: A study published in the Journal of Gastroenterology and Hepatology found that domperidone was significantly more effective than a placebo in reducing symptoms of gastroparesis. Another study in the European Journal of Gastroenterology & Hepatology showed that domperidone improved symptoms of functional dyspepsia compared to baseline.