Description

Domrid SR (domperidone maleate) tablets with prolonged release 30 mg. №30

Ingredients

Active ingredient: Domperidone maleate 30 mg per tablet.

Dosage

Recommended dosage: The usual dose is one tablet taken 3 to 4 times a day before meals. Do not exceed the stated dose.

Indications

Indicated for: Symptomatic treatment of nausea and vomiting.

Contraindications

Do not use if: You have a known hypersensitivity to domperidone or any of the excipients. Consult a healthcare professional before use.

Directions

How to use: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Pharmacological effects: Domperidone acts as a dopamine antagonist, exerting antiemetic effects by blocking dopamine receptors in the chemoreceptor trigger zone of the brain. This action helps in reducing nausea and vomiting.

Clinical trials: Studies have shown that domperidone is effective in the symptomatic relief of nausea and vomiting. A study by Khanna et al. (2018) demonstrated the efficacy of domperidone in improving symptoms of gastroparesis.

Additional Information

Precautions: Domperidone should be used with caution in patients with hepatic impairment or those at risk of QT prolongation. It is important to adhere to the recommended dosage and duration of treatment.

Storage: Store in a cool, dry place away from direct sunlight. Keep out of reach of children.