Description
Donormil (Doxylamine Succinate) Coated Tablets 15 mg. №10 Vial
Ingredients
Active ingredient: Doxylamine succinate 15 mg per tablet.
Mechanism of Action
Donormil contains doxylamine succinate, which acts as a histamine H1 receptor antagonist. By blocking histamine receptors in the brain, it inhibits wakefulness-promoting signals, leading to sedation and improved sleep onset and duration.
Pharmacological Properties
As a sedating antihistamine, doxylamine succinate exerts its effects by crossing the blood-brain barrier and antagonizing histamine receptors in the central nervous system. This results in sedative and hypnotic effects, making it effective in treating insomnia.
Indications for Use
Donormil tablets are indicated for the short-term treatment of insomnia in adults who have difficulty falling asleep or staying asleep.
Contraindications
Do not use Donormil if:
- You are allergic to doxylamine succinate or any other ingredients in the product.
- You have narrow-angle glaucoma.
- You are pregnant or breastfeeding.
Side Effects
Common side effects of Donormil may include drowsiness, dry mouth, blurred vision, constipation, and urinary retention. In rare cases, it may cause allergic reactions or paradoxical reactions such as agitation or hallucinations.
Usage Instructions
Adults: Take 1 tablet (15 mg) orally 30 minutes before bedtime. Do not exceed the recommended dose. Swallow the tablet whole with water and do not crush or chew it. Avoid alcohol consumption while using Donormil.
Benefits Compared to Analogues
Donormil offers a potent sedative effect with a lower risk of next-day drowsiness compared to some other sedating antihistamines. Its rapid onset of action and efficacy in improving sleep quality make it a preferred choice for short-term insomnia treatment.
Suitable Patient Groups
Donormil is suitable for use in adult patients experiencing transient insomnia. It is not recommended for children, elderly individuals, or individuals with certain medical conditions without medical supervision.
Storage and Shelf Life
Store Donormil in a cool, dry place away from direct sunlight. Keep the vial tightly closed to protect the tablets from moisture. Check the expiration date on the packaging and do not use the product after the specified shelf life.
Packaging Description
Donormil is supplied in a vial containing 10 coated tablets, each with 15 mg of doxylamine succinate. The vial is designed to maintain the stability and integrity of the tablets throughout the storage period.
Scientific Evidence
Studies have shown that doxylamine succinate, the active ingredient in Donormil, is effective in improving sleep onset and duration. A study published in the Journal of Clinical Sleep Medicine demonstrated that doxylamine succinate significantly reduced the time taken to fall asleep and improved overall sleep quality in patients with insomnia.
Additional Information
Donormil is a non-prescription medication commonly used for the short-term relief of insomnia. It works by blocking the action of histamine, a neurotransmitter involved in wakefulness, leading to sedation and improved sleep. Clinical trials have shown that Donormil is well-tolerated and effective in promoting sleep without causing significant next-day drowsiness. It is important to follow the recommended dosage and not exceed the prescribed amount to avoid adverse effects. If insomnia persists, consult a healthcare professional for further evaluation and treatment options.
