Description

Doxorubicin (doxorubicin) solution for infusions 2 mg/ml. 25 ml. (50 mg.) №1 vial

Ingredients:

Each ml contains 2 mg of Doxorubicin hydrochloride.

Dosage:

The dosage is determined by the prescribing healthcare provider based on individual factors such as body surface area, overall health, and the specific condition being treated.

Indications:

Doxorubicin is indicated for the treatment of various types of cancers including breast cancer, lung cancer, ovarian cancer, and soft tissue sarcomas.

Contraindications:

This medication is contraindicated in patients with severe myelosuppression, severe hepatic impairment, and hypersensitivity to Doxorubicin or any of its components.

Directions:

Doxorubicin is administered intravenously by a healthcare professional in a clinical setting. The infusion rate and duration are carefully monitored to minimize the risk of adverse effects.

Scientific Evidence:

Doxorubicin, a potent anthracycline antibiotic, exerts its antitumor effects by intercalating into DNA strands and inhibiting topoisomerase II, leading to DNA damage and apoptosis in cancer cells. Numerous studies have demonstrated the efficacy of Doxorubicin in various cancers, showing significant tumor regression and improved survival rates in patients.

One study published in the Journal of Clinical Oncology reported that Doxorubicin-based chemotherapy regimens were highly effective in treating advanced breast cancer, with a response rate of over 60% and a median survival of more than 18 months.

Additional Information:

• Adverse Effects: Common side effects of Doxorubicin include nausea, vomiting, hair loss, and myelosuppression. Regular monitoring of cardiac function is essential due to the potential cardiotoxicity of this medication.
• Storage: Store Doxorubicin vials in a cool, dry place away from light and moisture. Keep out of reach of children.