Description

Drotaverin Forte Tablets 80 mg. №10

Ingredients:

Each tablet contains 80 mg of Drotaverine hydrochloride.

Dosage:

The recommended dosage is one tablet (80 mg) taken orally up to three times a day.

Indications:

Drotaverin Forte tablets are indicated for the treatment of smooth muscle spasms associated with conditions such as irritable bowel syndrome, biliary colic, and menstrual cramps.

Contraindications:

Do not use Drotaverin Forte tablets if you have a known hypersensitivity to Drotaverine or any other ingredients in the formulation.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence:

Drotaverine is a selective inhibitor of phosphodiesterase 4 (PDE4) and has been shown to effectively relax smooth muscles by inhibiting the hydrolysis of cyclic adenosine monophosphate (cAMP). This mechanism of action results in vasodilation and decreased smooth muscle contractions, providing relief from spasms.

Several clinical studies have demonstrated the efficacy of Drotaverin in the treatment of various smooth muscle spasms. A study published in the International Journal of Gastroenterology showed that Drotaverin was effective in reducing the frequency and intensity of irritable bowel syndrome symptoms compared to a placebo.

Additional Information:

Drotaverin Forte tablets are well-tolerated by most patients, with minimal side effects such as dizziness or gastrointestinal disturbances reported in rare cases. It is important to follow the prescribed dosage and not exceed the recommended frequency of administration.

Before using Drotaverin Forte tablets, consult with a healthcare professional, especially if you have any underlying medical conditions or are taking other medications to avoid potential drug interactions.