Description

Drotaverin Tablets 0.04 g. №10

Ingredients

Active ingredient: Drotaverine hydrochloride 40 mg per tablet.

Dosage

Dosage: The usual dose is 1 tablet (40 mg) taken orally 3-4 times a day after meals. Do not exceed the recommended dosage.

Indications

Indications: Drotaverin is indicated for the treatment of smooth muscle spasms associated with conditions such as abdominal pain, menstrual cramps, and irritable bowel syndrome.

Contraindications

Contraindications: Do not use Drotaverin if you are allergic to drotaverine or if you have severe liver or kidney disease.

Directions

– Take the tablet orally with water.
– Do not crush or chew the tablet.
– Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Drotaverin, a smooth muscle relaxant, has shown efficacy in various clinical studies. A study published in the International Journal of Gynecology & Obstetrics demonstrated the effectiveness of drotaverine in reducing the intensity and duration of menstrual pain. Another study in the European Journal of Gastroenterology & Hepatology highlighted its benefits in relieving abdominal pain associated with irritable bowel syndrome.

Additional Information

Drotaverin works by inhibiting the enzyme phosphodiesterase, leading to relaxation of smooth muscles. This action helps to alleviate spasms and improve blood flow in affected areas. Compared to other spasmolytic agents, drotaverin has shown a favorable safety profile with minimal side effects such as dizziness or dry mouth.

Pharmacological Effects: Drotaverin acts directly on smooth muscles, causing relaxation and relief from spasms. It does not affect the autonomic nervous system, making it a targeted and effective treatment for smooth muscle-related conditions.

Clinical Trials: Clinical trials have demonstrated the superior efficacy of drotaverin in comparison to traditional antispasmodic agents. Its rapid onset of action and sustained relief make it a preferred choice for patients suffering from acute abdominal pain or menstrual cramps.