Description

Dufalak Frut (lactulose) oral solution 667 mg/ml. 200 ml. vial

Ingredients

Active ingredient: Lactulose
Inactive ingredients: purified water, fruit flavoring

Dosage

Adults and children over 14 years: 15-45 ml daily, adjusted according to individual response.
Children 7-14 years: 15 ml daily.
Children 1-6 years: 5-10 ml daily.

Indications

Dufalak Frut oral solution is indicated for the treatment of constipation and hepatic encephalopathy.

Contraindications

Do not use Dufalak Frut oral solution if you are allergic to lactulose or any of the ingredients. Consult a healthcare professional before use if pregnant or breastfeeding.

Directions

Shake well before use. Take orally. Can be taken with or without food. Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Lactulose, the active ingredient in Dufalak Frut oral solution, is a synthetic disaccharide that is not absorbed in the small intestine but is fermented by gut bacteria in the colon. This fermentation process leads to an increase in osmotic pressure and acidification of the colonic contents, resulting in improved bowel movements. Studies have shown that lactulose is effective in the treatment of constipation and hepatic encephalopathy by promoting the growth of beneficial gut bacteria and reducing the production of toxic substances in the gut.

Additional Information

It is important to drink an adequate amount of water while using Dufalak Frut oral solution to prevent dehydration. Avoid using laxatives or other medications that may interact with lactulose without consulting a healthcare provider. If symptoms persist or worsen, seek medical advice.

Pharmacological Effects: Lactulose works by drawing water into the colon, softening the stool and increasing bowel movements. It also promotes the growth of beneficial bacteria in the gut, which can help improve overall gut health.

Clinical Trials: Clinical trials have demonstrated the efficacy of lactulose in the treatment of constipation and hepatic encephalopathy. A study published in the Journal of Gastroenterology and Hepatology found that lactulose was effective in improving stool frequency and consistency in patients with chronic constipation.