Description
Duodart (dutasteride/tamsulosin) Hard Capsules 0.5 mg/0.4 mg – Pack of 90
Composition
Each hard capsule contains 0.5 mg of dutasteride and 0.4 mg of tamsulosin hydrochloride.
Mechanism of Action
Duodart combines dutasteride, a 5-alpha-reductase inhibitor, with tamsulosin, an alpha-blocker. Dutasteride inhibits the conversion of testosterone to dihydrotestosterone, reducing prostate size. Tamsulosin relaxes the muscles in the prostate and bladder neck, improving urine flow.
Pharmacological Properties
The pharmacological properties of Duodart result from the complementary actions of dutasteride and tamsulosin, targeting different aspects of benign prostatic hyperplasia (BPH) to alleviate symptoms and improve urinary flow.
Indications for Use
Duodart is indicated for the treatment of symptomatic BPH in adult men with an enlarged prostate, helping to reduce prostate size and improve urinary symptoms.
Contraindications
Avoid Duodart if you are allergic to dutasteride, tamsulosin, or any other components of the capsules. Consult your healthcare provider for alternative treatment options.
Side Effects
Possible side effects of Duodart include dizziness, decreased libido, and erectile dysfunction. Contact your doctor if you experience any adverse reactions while taking this medication.
Usage Instructions
Take one Duodart capsule daily, whole with a glass of water, as directed by your healthcare provider. Adhere to the prescribed dosage and do not exceed the recommended amount.
Benefits Compared to Analogues
Duodart’s dual therapy approach offers a more comprehensive treatment for BPH compared to single-agent therapies. The combination of dutasteride and tamsulosin provides synergistic benefits in managing BPH symptoms.
Suitable Patient Groups
Duodart is suitable for adult men with symptomatic BPH and an enlarged prostate. It is essential to follow dosage instructions and consult a healthcare professional for personalized treatment recommendations.
Storage and Shelf Life
Store Duodart in a cool, dry place away from moisture and sunlight. Check the expiration date on the packaging and do not use the product beyond the specified shelf life.
Packaging Description
Duodart is available in a pack containing 90 hard capsules, each clearly labeled with the dosage strength and ingredients for easy identification.
Clinical Evidence and Proven Effectiveness
Duodart has been clinically proven to effectively improve symptoms of BPH, reduce the risk of acute urinary retention, and lower the need for BPH-related surgery. Studies, including research published in the Journal of Urology, demonstrate the superior efficacy of the dutasteride and tamsulosin combination in enhancing urinary symptoms and flow rates in men with BPH.
