Duovit coated tablets №60

Description

Duovit Composition
active ingredients:

1 red film-coated tablet contains:

vitamin A (retinol palmitate) – 5000 IU;
vitamin D3 (cholecalciferol) – 200 IU;
vitamin C (ascorbic acid) – 60 mg;
vitamin PP (nicotinamide) – 13 mg;
vitamin E (a-tocopherol acetate) – 10 mg;
calcium pantothenate – 5 mg;
vitamin B6 (pyridoxine hydrochloride) – 2 mg;
vitamin B2 (riboflavin) – 1.2 mg;
vitamin B1 (thiamine nitrate) – 1 mg;
folic acid – 0.4 mg;
vitamin B12 (cyanocobalamin) – 3 mcg.
excipients: lactose, orange oil flavoring, polysorbate 80, glycerin, castor oil, sorbitol (E 420), glucose solution, magnesium stearate, capol 600 pharma (contains yellow wax, carnauba wax, shellac), defoaming agent, Opalux AS-F -2833G (contains sunset yellow dye FCF (E 110), povidone, sucrose, ponceau dye 4R (E124), titanium dioxide, sodium benzoate (E 211), purified water), sucrose, mannitol (E 421)

Duovit Dosage form
Film-coated tablets.

Basic physical and chemical properties: hard, smooth red coated tablets with a sweet and sour taste and possible inclusions on the surface; hard, smooth blue film-coated tablets with possible inclusions on the surface.

Duovit Pharmacotherapeutic group
Multivitamins with trace elements. ATX code A11A A04.

Pharmacodynamics
Duovit, film-coated tablets containing vitamins and minerals. Vitamins and minerals are closely related in their functional activity and exhibit an additive effect. Some vitamins and minerals cannot coexist, which is why they are separated in red (vitamins) and blue (minerals) Duovit tablets.

B vitamins (B1, B2, B6, pantothenic acid and nicotinamide) are involved in the metabolism of carbohydrates, proteins and fats, and they are also involved in the functioning of the nervous system. Vitamin B12 is involved in erythropoiesis, contributes to the normal functioning of the nervous system. Vitamin A is essential for the development of epithelial cells and for the synthesis of visual pigment. Vitamin D3 regulates calcium absorption and promotes proper mineralization of bones and teeth. Vitamin C controls the absorption of iron and is involved in redox processes in the body. Vitamin E, a physiological antioxidant, protects cell membranes from damage and maintains their functionality.

Minerals and oligoelements are very important for the body. They are constituents of tissues or activators and constituents of enzymes and hormones. Calcium and phosphorus play an important role in the mineralization of bones and teeth. Calcium ions activate many enzymes involved in the regulation of the tone of the heart muscle, in the transmission of nerve impulses and regulate the permeability of cell membranes. Iron and copper, along with B vitamins, are important for the formation of red blood cells. Magnesium, manganese, zinc and molybdenum play the role of enzyme constituents in many reactions that are important for the body.

Pharmacokinetics
There is no available data on the pharmacokinetics of Duovit tablets. However, in the scientific literature there is information about the absorption, distribution and excretion of certain vitamins and minerals.

Water-soluble vitamins (B vitamins, vitamin C) are absorbed within the daily requirement. Amounts exceeding tissue absorption are excreted in the urine, in some cases also in the faeces. These vitamins are found in very small amounts in the body, therefore, their proper level in the body must be maintained.

After oral administration, fat-soluble vitamins A and D3 are absorbed in the small intestine in the presence of fats. The absorption of vitamin E is relatively low (25% to 85% of the dose). These vitamins are stored in large quantities in the liver and therefore are also toxic than water-soluble vitamins.

Indications
Duovit film-coated tablets are recommended:

with physical and mental overload (while studying, at work or at home);
when practicing active sports and outdoor activities;
in case of disorders in the assimilation of nutrients (when drinking alcohol, smoking, in the elderly);
with inadequate and unbalanced nutrition;
while dieting (weight loss diet and other types of diets);
during periods of seasonal deficiency of fruits and vegetables in the diet;
with a significant loss of minerals (due to vomiting, diarrhea, excessive menstruation, increased sweating).

Contraindications
Hypersensitivity to the components of the drug, hypervitaminosis of vitamins A, E and D3, renal failure, severe renal dysfunction. Concomitant use of retinoids. Nephrolithiasis, gout, hyperuricemia, erythremia, erythrocytosis, thrombophlebitis, thromboembolism, fructose intolerance, glucose-galactose malabsorption syndrome, malabsorption of iron or copper, hypercalcemia, hypercalciuria, hypermagnesemia, thyrotoxicosis cardiac disease, chronic groma stomach and duodenum in the acute stage (due to a possible increase in gastric acidity), active forms of tuberculosis.

Do not use in children (under the age of 18).