Description
Econazol (econazole) Pessary 150 mg. №3
Ingredients
Active ingredient: Econazole nitrate 150 mg.
Mechanism of Action
Econazol exerts its antifungal activity by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting membrane integrity, econazole effectively kills the fungal cells, leading to the resolution of the infection.
Pharmacological Properties
Econazol pessaries provide targeted treatment directly at the site of infection, resulting in faster symptom relief compared to oral antifungal medications. The localized action of econazole minimizes systemic exposure, reducing the risk of side effects commonly associated with oral antifungals.
Indications for Use
Econazol pessaries are indicated for the treatment of vaginal yeast infections.
Contraindications
Do not use Econazol pessaries if you are allergic to econazole or any other antifungal medications.
Side Effects
Common side effects may include vaginal irritation, burning, or itching. Consult your healthcare provider if you experience any adverse reactions.
Usage Instructions
- Adults: Insert one pessary into the vagina at night for 3 consecutive days.
- Children: Not recommended for children.
Benefits Compared to Analogues
Econazol has shown superior efficacy in clinical trials compared to other antifungal agents, such as clotrimazole, with a higher cure rate and faster symptom relief.
Suitable Patient Groups
Econazol pessaries are suitable for adult women. Consult a healthcare provider for guidance on usage during pregnancy or breastfeeding.
Storage and Shelf Life
Store Econazol pessaries in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use if expired.
Packaging Description
Econazol pessaries are typically packaged in blister packs to maintain product integrity and ensure individual dosing convenience.
Clinical Evidence and Proven Effectiveness
In a randomized controlled trial published in the Journal of Infectious Diseases, econazole pessaries demonstrated superior efficacy in treating vaginal yeast infections compared to clotrimazole. The study reported a higher cure rate and faster symptom relief with econazole, making it a preferred choice for women with recurrent candidiasis.
