Description

Econazol (econazole) pessary 150 mg. №3

Ingredients

Active ingredient: Econazole nitrate 150 mg.

Dosage

Adults: Insert one pessary into the vagina at night for 3 consecutive days.
Children: Not recommended for children.

Indications

Econazol pessaries are indicated for the treatment of vaginal yeast infections.

Contraindications

Do not use Econazol pessaries if you are allergic to econazole or any other antifungal medications.

Directions

1. Wash your hands before and after use.
2. Lie on your back with bent knees and insert the pessary deep into the vagina.
3. Wash the applicator thoroughly after each use.

Scientific Evidence

Econazol (econazole) has been extensively studied for its antifungal properties. Research published in the Journal of Antimicrobial Chemotherapy demonstrated the efficacy of econazole in treating various fungal infections, including vaginal candidiasis. The study highlighted econazole’s high potency against Candida species, making it a valuable treatment option.

Additional Information

Econazol pessaries provide targeted treatment directly at the site of infection, resulting in faster symptom relief compared to oral antifungal medications. The localized action of econazole minimizes systemic exposure, reducing the risk of side effects commonly associated with oral antifungals. Consult your healthcare provider before using econazole pessaries, especially if you are pregnant or breastfeeding.

Pharmacological Effects:

Econazol exerts its antifungal activity by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting membrane integrity, econazole effectively kills the fungal cells, leading to the resolution of the infection.

Clinical Trials:

In a randomized controlled trial published in the Journal of Infectious Diseases, econazole pessaries demonstrated superior efficacy in treating vaginal yeast infections compared to clotrimazole, another commonly used antifungal agent. The study reported a higher cure rate and faster symptom relief with econazole, making it a preferred choice for women with recurrent candidiasis.