Description
Ecvator (lisinopril, amlodipine) 20 mg/10 mg Tablets №30
Ingredients
Each tablet contains: 20 mg of lisinopril and 10 mg of amlodipine.
Mechanism of Action
Ecvator (lisinopril, amlodipine) acts by: Lisinopril, an ACE inhibitor, works by relaxing blood vessels, while amlodipine, a calcium channel blocker, helps to widen the blood vessels, resulting in improved blood flow and reduced blood pressure. This dual mechanism of action makes Ecvator an effective antihypertensive medication.
Pharmacological Properties
Ecvator combines the actions of lisinopril and amlodipine to effectively manage hypertension. Lisinopril inhibits angiotensin-converting enzyme (ACE), leading to vasodilation and reduced blood pressure. Amlodipine blocks calcium channels in vascular smooth muscle, resulting in vasodilation and decreased peripheral resistance.
Indications for Use
Ecvator tablets are indicated for:
- Treatment of hypertension
- Reduction of the risk of stroke and heart attacks in patients with hypertension
Contraindications
Do not use Ecvator if:
- You are allergic to lisinopril, amlodipine, or any other ingredients in the product
- You have a history of angioedema related to previous ACE inhibitor treatment
Side Effects
Common side effects of Ecvator may include dizziness, cough, edema, and flushing. Severe side effects such as angioedema and hypotension may occur in some individuals. Consult a healthcare provider if any adverse reactions are experienced.
Usage Instructions
The recommended dosage: Take one tablet orally once a day, with or without food, or as directed by a healthcare professional.
Directions:
- Swallow the tablet whole with a glass of water
- Do not crush or chew the tablet
Benefits Compared to Analogues
Ecvator has demonstrated superior efficacy in managing hypertension and reducing cardiovascular risks compared to monotherapy options. The combination of lisinopril and amlodipine provides enhanced blood pressure control and cardiovascular protection.
Suitable Patient Groups
Ecvator is suitable for adult patients with hypertension. It may be prescribed for elderly individuals and those with comorbidities such as diabetes or chronic kidney disease under medical supervision. Use in children should be determined by a healthcare provider.
Storage and Shelf Life
Store Ecvator tablets at room temperature away from moisture and heat. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use expired tablets.
Packaging Description
Ecvator tablets are supplied in a package containing 30 tablets. The packaging is designed to protect the tablets from environmental factors and maintain their integrity until use.
Clinical Evidence and Proven Effectiveness
Ecvator (lisinopril, amlodipine) has shown significant efficacy in managing hypertension and reducing cardiovascular risks. Studies have demonstrated that the combination of lisinopril and amlodipine provides better blood pressure control compared to monotherapy. Research published in the Journal of Clinical Hypertension highlighted the superior efficacy of the lisinopril-amlodipine combination in lowering blood pressure levels in hypertensive patients.
Additional Information
It is essential to monitor blood pressure regularly while taking Ecvator tablets. Consult your healthcare provider if you experience any side effects or have concerns about the medication. Inform your doctor about all the medications you are currently taking to avoid potential drug interactions.
