Description

Edem (desloratadine) Coated Tablets 5 mg. №10

Ingredients

Each tablet contains 5 mg of desloratadine.

Dosage

The recommended dosage for adults and children over 12 years old is one tablet once daily.

Indications

Edem tablets are indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria.

Contraindications

Do not use Edem tablets if you are allergic to desloratadine or any other ingredients in the formulation.

Directions

Swallow the tablet whole with water, with or without food.

Scientific Evidence

Desloratadine, the active ingredient in Edem tablets, is a selective H1-antihistamine that works by blocking the action of histamine in the body. Histamine is a chemical released during an allergic reaction, causing symptoms like sneezing, itching, and watery eyes. Clinical studies have shown that desloratadine is effective in relieving these symptoms with a low incidence of sedation, making it a preferred choice for many patients.

Additional Information

It is important to note that while Edem tablets provide relief from allergy symptoms, they may not be suitable for everyone. Patients with severe liver impairment or kidney disease should consult their healthcare provider before using this medication. Additionally, desloratadine may interact with certain medications, so it is essential to inform your doctor about all the drugs you are taking.

Pharmacological Effects and Clinical Trials

Desloratadine, the active metabolite of loratadine, exhibits potent antihistaminic properties with minimal sedative effects. It has a rapid onset of action, providing relief from allergy symptoms within 30 minutes of administration. Clinical trials have demonstrated the efficacy of desloratadine in improving quality of life and reducing the severity of symptoms in patients with allergic rhinitis and chronic urticaria.

Compared to other second-generation antihistamines, desloratadine has shown similar efficacy in symptom relief with a lower incidence of side effects such as sedation and dry mouth. Its once-daily dosing regimen offers convenience and improved compliance for patients.