Description
Efferalgan (Paracetamol) Suppositories 150 mg. №10
Ingredients
Active ingredient: Each suppository contains 150 mg of paracetamol.
Mechanism of Action
Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system, which helps to reduce pain and lower fever.
Pharmacological Properties
Paracetamol is a centrally acting analgesic and antipyretic agent that exhibits minimal anti-inflammatory effects. It is rapidly absorbed after rectal administration, providing quick onset of action.
Indications for Use
Indications: Efferalgan suppositories are indicated for the relief of mild to moderate pain such as headache, toothache, muscle aches, and reduction of fever in various conditions.
Contraindications
Contraindications: Do not use Efferalgan suppositories in individuals with known hypersensitivity to paracetamol or any other component of the suppository. Avoid use in patients with severe hepatic impairment or alcohol dependence.
Side Effects
Common side effects of paracetamol suppositories may include nausea, vomiting, and allergic reactions. In rare cases, it can lead to liver damage if used in high doses or for prolonged periods.
Usage Instructions
Dosage: The usual dose is one suppository (150 mg) every 4 to 6 hours as needed. Do not exceed 4 doses in 24 hours. Wash hands before and after use. Insert the suppository into the rectum and allow it to dissolve completely.
Benefits Compared to Analogues
Efferalgan suppositories offer a convenient and effective alternative to oral paracetamol formulations, especially for patients who have difficulty swallowing or are unable to take medications orally. The rectal route of administration ensures rapid absorption and onset of action.
Suitable Patient Groups
Efferalgan suppositories are suitable for use in adults, adolescents, and children who are unable to take oral medications. They are particularly beneficial for elderly patients and individuals with swallowing difficulties.
Storage and Shelf Life
- Storage: Store Efferalgan suppositories in a cool, dry place away from direct sunlight.
- Shelf Life: Check the expiration date on the packaging. Do not use after the expiry date.
Packaging Description
Efferalgan suppositories are individually wrapped in foil packaging to maintain their integrity and ensure sterility. Each box contains 10 suppositories.
Clinical Evidence and Proven Effectiveness
Paracetamol’s Efficacy: Paracetamol is a widely recognized and extensively studied analgesic and antipyretic medication with a well-established safety profile. Clinical studies have consistently demonstrated its efficacy in managing pain and reducing fever in various clinical settings.
Clinical Trials: Clinical trials have shown that paracetamol suppositories provide rapid and effective relief from pain and fever, with outcomes comparable to oral formulations. The rectal route of administration offers a reliable alternative for patients who cannot take medications orally, ensuring optimal therapeutic outcomes.
