Description

Eficold (paracetamol, caffeine) Effervescent Tablets 500 mg/50 mg. №32

Ingredients

Each effervescent tablet contains:

• Paracetamol 500 mg
• Caffeine 50 mg

Dosage

Adults and children over 12 years: Dissolve 1 tablet in a glass of water every 4-6 hours as needed. Do not exceed 4 tablets in 24 hours.

Indications

Eficold effervescent tablets are indicated for the relief of mild to moderate pain such as headaches, toothaches, and menstrual cramps. The caffeine component helps to enhance the analgesic effect of paracetamol.

Contraindications

Do not use Eficold tablets if you:

• Are allergic to paracetamol or caffeine
• Have severe liver or kidney disease
• Are pregnant or breastfeeding

Directions

Dissolve the tablet in a glass of water before taking it orally. Do not chew the tablet. Consult a healthcare professional if symptoms persist.

Scientific Evidence

Paracetamol: Paracetamol is a well-established analgesic and antipyretic medication with a proven safety profile. Studies have shown its effectiveness in managing various types of pain.

Caffeine: Caffeine is known to enhance the pain-relieving effects of analgesics like paracetamol. It acts centrally to increase alertness and improve concentration.

Additional Information

Pharmacological Effects: The combination of paracetamol and caffeine in Eficold tablets provides a synergistic effect in pain relief. Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system, while caffeine acts as a central nervous system stimulant.

Clinical Trials: Clinical trials have demonstrated the efficacy of paracetamol-caffeine combinations in providing rapid and effective relief from various types of pain, with a lower risk of gastrointestinal side effects compared to other pain medications.