Description
Egylok (Metoprolol) Tablets 25 mg. №60 Vial
Ingredients:
Each tablet contains 25 mg of metoprolol tartrate.
Mechanism of Action:
Metoprolol, a selective beta-1 adrenergic receptor blocker, works by competitively blocking the effects of catecholamines like epinephrine on the heart. This leads to decreased heart rate, reduced myocardial contractility, and lowered blood pressure.
Pharmacological Properties:
Metoprolol exhibits anti-hypertensive, anti-anginal, and antiarrhythmic properties. It selectively acts on cardiac beta-1 receptors, resulting in decreased cardiac output and oxygen consumption.
Indications for Use:
- Treatment of hypertension
- Management of angina pectoris
- Improvement of heart failure symptoms
Contraindications:
Do not administer Egylok in patients with:
- Heart rate less than 45 beats per minute
- Greater than first-degree heart block
- Severe heart failure
Side Effects:
Common side effects of metoprolol may include fatigue, dizziness, bradycardia, and gastrointestinal disturbances. Rare but serious side effects may include bronchospasm and heart block.
Usage Instructions:
The typical starting dosage is 25 mg once daily, with the option to increase up to 100-450 mg daily in divided doses as directed by a healthcare professional.
Benefits Compared to Analogues:
Egylok offers advantages over other beta-blockers due to its selective beta-1 receptor blockade, leading to effective management of cardiovascular conditions with potentially fewer side effects on bronchial and vascular smooth muscle.
Suitable Patient Groups:
Egylok can be used in various patient populations, including adults, elderly individuals, and selected pediatric cases under close medical supervision.
Storage Conditions and Shelf Life:
Store Egylok tablets at room temperature away from moisture and heat. Check the packaging for the expiration date and do not use the product beyond that date.
Packaging Description:
Egylok is available in a vial containing 60 tablets of 25 mg strength each, ensuring an adequate supply for the prescribed duration.
Clinical Evidence and Proven Effectiveness:
Studies have demonstrated the efficacy of metoprolol in reducing blood pressure, alleviating angina symptoms, and improving cardiac function in patients with heart failure. Notably, research published in the Journal of the American College of Cardiology highlighted the mortality and hospitalization benefits associated with metoprolol therapy in heart failure patients.
