Description
Enap (enalapril maleate) tablets 10 mg. №60
Ingredients:
Enap tablets contain 10 mg of enalapril maleate as the active ingredient.
Mechanism of Action:
Enap tablets work by inhibiting the angiotensin-converting enzyme, leading to vasodilation, decreased aldosterone secretion, and reduced sodium reabsorption, resulting in lowered blood pressure and improved cardiac function.
Pharmacological Properties:
Enalapril maleate is an angiotensin-converting enzyme (ACE) inhibitor that selectively inhibits the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This action leads to vasodilation and reduced aldosterone secretion.
Indications for Use:
Enap tablets are indicated for the management of hypertension, congestive heart failure, and increasing survival post-myocardial infarction.
Contraindications:
Do not use Enap tablets if you have a history of angioedema related to previous ACE inhibitor use, are pregnant, or have severe renal artery stenosis.
Side Effects:
Common side effects of Enap tablets may include dizziness, cough, hypotension, and hyperkalemia. Serious but rare side effects may include angioedema and renal impairment.
Usage Instructions:
The recommended dosage of Enap tablets is one 10 mg tablet taken orally once daily. Dosage adjustments may be necessary based on individual patient response and renal function.
Benefits Compared to Analogues:
Enalapril has demonstrated similar efficacy to other ACE inhibitors in managing hypertension and heart failure, with a preferable side effect profile. Its proven benefits in post-myocardial infarction patients make it a valuable choice in cardiovascular therapy.
Suitable Patient Groups:
Enap tablets are suitable for adult patients with hypertension, heart failure, or a history of myocardial infarction. Dosage adjustments may be required for elderly patients or those with renal impairment.
Storage and Shelf Life:
Store Enap tablets in a cool, dry place at room temperature. Protect from light and moisture. Check the expiration date on the packaging and do not use beyond the stated shelf life.
Packaging Description:
Enap tablets are available in a pack of 60 tablets. Each tablet is film-coated for ease of swallowing and protection from degradation.
Scientific Evidence:
Studies have shown that enalapril effectively reduces blood pressure, improves cardiac function, and enhances survival rates in cardiovascular patients. Meta-analyses support the role of ACE inhibitors, including enalapril, in heart failure and post-myocardial infarction care.
