Description
Enap (Enalapril Maleate) Tablets 2.5 mg. №20
Ingredients
Active ingredient: Enalapril maleate 2.5 mg per tablet.
Mechanism of Action
Enap works by inhibiting the angiotensin-converting enzyme, which plays a key role in regulating blood pressure and fluid balance in the body. By blocking this enzyme, Enap helps to dilate blood vessels and reduce the workload on the heart, leading to improved cardiovascular function.
Pharmacological Properties
Enalapril maleate, the active ingredient in Enap, is an angiotensin-converting enzyme (ACE) inhibitor. It acts by preventing the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, resulting in vasodilation and decreased aldosterone secretion.
Indications for Use
Indications: Enap is indicated for the treatment of hypertension and heart failure.
Contraindications
Contraindications: Do not use Enap if you are allergic to enalapril or any other ACE inhibitor. It is important to consult with a healthcare provider before starting Enap to ensure it is safe and appropriate for you.
Side Effects
Common side effects of Enap may include dizziness, cough, hypotension, and hyperkalemia. Serious side effects such as angioedema and renal impairment are rare but require immediate medical attention.
Usage Instructions
Dosage: The usual starting dose is 2.5 mg once a day. Dosage may be adjusted according to the individual’s response. Take Enap exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water.
Benefits Compared to Analogues
Enap offers the advantage of proven efficacy and safety in the management of hypertension and heart failure compared to other ACE inhibitors. Its once-daily dosing regimen provides convenience and improved adherence for patients.
Suitable Patient Groups
Enap is suitable for adult patients with hypertension and heart failure. It may be used in elderly patients and those with renal impairment under close medical supervision. Enap is not recommended for use in children.
Storage and Shelf Life
Store Enap tablets in a cool, dry place away from direct sunlight. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description
Enap tablets are packaged in blister packs containing 20 tablets each. The packaging is designed to protect the tablets from moisture and external factors that may affect their stability.
Clinical Evidence and Proven Effectiveness
Enalapril, the active ingredient in Enap, is supported by extensive clinical evidence demonstrating its efficacy in lowering blood pressure and improving cardiac function in patients with hypertension and heart failure. Clinical studies have shown significant reductions in blood pressure levels and improvements in left ventricular function with the use of Enap.