Description
Enap HL (Enalapril Maleate and Hydrochlorothiazide) Tablets 10 mg/12.5 mg – Pack of 60 Tablets
Composition
Each tablet contains:
- Enalapril Maleate: 10 mg
- Hydrochlorothiazide: 12.5 mg
Mechanism of Action
Enap HL tablets combine the effects of enalapril maleate and hydrochlorothiazide. Enalapril inhibits the angiotensin-converting enzyme, leading to vasodilation and decreased blood pressure. Hydrochlorothiazide, a diuretic, promotes the elimination of excess salt and water, further reducing blood pressure.
Pharmacological Properties
The synergistic action of enalapril and hydrochlorothiazide in Enap HL tablets effectively manages hypertension by lowering blood pressure through vasodilation and diuresis.
Indications for Use
Enap HL tablets are indicated for the treatment of hypertension in cases where treatment with enalapril alone is insufficient to control blood pressure levels.
Contraindications
Avoid using Enap HL tablets if:
- You are allergic to enalapril, hydrochlorothiazide, or any other tablet ingredients.
- You have a history of angioedema associated with previous ACE inhibitor therapy.
Side Effects
Possible side effects of Enap HL tablets include dizziness, lightheadedness, and swelling. Contact your healthcare provider if you experience any of these symptoms.
Usage Instructions
Take one Enap HL tablet orally daily, with or without food. Swallow the tablet whole with a glass of water. Follow the instructions provided by your healthcare provider.
Benefits Compared to Analogues
Enap HL tablets offer enhanced efficacy in managing hypertension compared to using enalapril or hydrochlorothiazide alone. The combination therapy provides better control over blood pressure levels.
Suitable Patient Groups
Enap HL tablets are suitable for adult patients with hypertension. Dosage adjustments may be necessary for specific patient populations such as the elderly or those with renal impairment. Consult a healthcare professional for personalized recommendations.
Storage and Shelf Life
Store Enap HL tablets in a cool, dry place away from direct sunlight. Check the packaging for the expiry date and do not use expired tablets.
Packaging Description
Each pack of Enap HL contains 60 tablets. The packaging is designed to protect the tablets from environmental factors and maintain their efficacy until the expiry date.
Clinical Evidence and Proven Effectiveness
Enalapril maleate and hydrochlorothiazide in Enap HL tablets have undergone extensive clinical studies to demonstrate their efficacy in managing hypertension. Clinical trials have shown that the combination therapy is more effective in reducing blood pressure than either drug alone. Patients using Enap HL have shown significant reductions in both systolic and diastolic blood pressure levels.
Additional Information
Regular monitoring of potassium levels is essential while taking Enap HL tablets, particularly in patients at risk of hypokalemia. Periodic blood pressure checks and kidney function tests are recommended during treatment to ensure optimal management of hypertension.