Enat-400 soft capsules 400 IU №30

Description

Enat-400 Storage
active substance: 1 capsule contains vitamin E – 400 IU (D-alpha-tocopheryl acetate);

Enat-400 excipients: soybean oil; gelatin capsule: gelatin, glycerin, purified water.

Enat-400 Dosage form
The capsules are soft.

Main physical and chemical properties: oval soft gelatin capsules filled with a clear light yellow oily liquid.

Pharmacotherapeutic group
Simple vitamin preparations. Tocopherol (vitamin E). ATX code A11H A03.

Pharmacological properties

Pharmacodynamics.

Vitamin E is a fat-soluble vitamin that has a high antioxidant and radioprotective effect, is involved in the biosynthesis of heme and proteins, cell proliferation and other important processes of cellular metabolism. Vitamin E improves tissue oxygen consumption. It has an angioprotective effect, affecting the tone and permeability of blood vessels, stimulating the formation of new capillaries.

The immunomodulatory effect of vitamin E is due to the stimulation of T-cell and humoral immunity.

Tocopherol is indispensable for normal reproductive processes: fertilization, fetal development, formation and functioning of the reproductive system.

Vitamin E deficiency develops hypotension and dystrophy of skeletal muscles, myocardium, increased permeability and fragility of capillaries, develops degeneration of photoreceptors, which causes visual impairment. Develops a decrease in sexual function in men and menstrual disorders, a tendency to miscarriage in women.

Vitamin E deficiency can cause the development of hemolytic jaundice in newborns, as well as malabsorption syndrome, steatorrhea.

Pharmacokinetics.

After absorption in the intestine, most of the tocopherol enters the lymph and blood, is rapidly distributed in body tissues with a predominant accumulation in the liver, muscles, adipose tissue. The highest concentration is observed in the adrenal glands, pituitary gland, gonads, myocardium. Most of the drug is excreted in the urine, in part – in the bile.

Indication
The drug is used as part of complex therapy to prevent disorders of fetal embryonic development, autonomic disorders or as an adjunct in the hormonal treatment of menstrual disorders.

Atrophic processes in the mucous membrane of the respiratory tract and digestive system. Used as an aid in neurosensory hearing disorders.

Neurasthenia in conditions accompanied by exhaustion, muscular dystrophy and muscle atrophy.

Degenerative and proliferative changes in the joints and fibrous tissue of the spine and large joints; secondary muscle weakness and myopathy in chronic arthritis, muscle weakness due to frequent recurrences of discogenic blockade.

It is used as an adjunct in some endocrine disorders and as a treatment in combination with vitamin A in infertility in men.

Eating disorders, malabsorption syndrome, nutritional anemia. Used in the treatment of chronic hepatitis.

Used as an adjunct in the treatment of some cases of periodontal disease.

Plastic induration of the penis, vulvar kraurosis, scleroderma, eczema, balanitis.

Used as part of antioxidant therapy.

Contraindication
Hypersensitivity to the active substance and to any components of the medicinal product; cardiosclerosis; acute period of myocardial infarction; thyrotoxicosis; hypervitaminosis E; hypersensitivity to peanuts or soy.