$36.00
Manufacturer: India
Replacement therapy for mild to moderate violations of the external secretory function of the pancreas in chronic pancreatitis (except in cases of exacerbation of chronic pancreatitis), to improve the digestive processes in ulcerative colitis, irritable bowel syndrome, as well as after gastric resection; flatulence and some cases of diarrhea of non-infectious origin; to improve the digestion of food for people with normal gastrointestinal function in case of violations of the regime of rational nutrition (eating a large amount of food, eating fatty, fried or unusual food, irregular eating); in case of violation of the chewing function, in conditions that lead to prolonged immobilization; preparation for x-ray and ultrasound examination of the abdominal cavity;
Description
Enzistal Storage
active substances: 1 tablet contains pancreatin 192 mg (lipase 6000 IU MFF, amylase 4500 IU MFF, protease 300 IU MFF), hemicellulase 50 mg, bile extract 25 mg;
Excipients:
lactose monohydrate, magnesium stearate, colloidal anhydrous silica, cellulose acetyl phthalate, diethyl phthalate, sugar, calcium carbonate, talc, acacia, gelatin, titanium dioxide (E 171), yellow wax.
Enzistal Dosage form
Sugar-coated tablets are enteric-coated.
Main physical and chemical properties: round biconvex tablets, coated with white sugar.
Pharmacotherapeutic group
Drugs that improve digestion, including enzymes. Polyenzyme preparations.
ATX code A09A A02.
Pharmacological properties
Pharmacodynamics.
Combined drug. The enzymes contained in the drug facilitate the digestion of proteins, fats, carbohydrates and promote a more complete absorption of the latter in the small intestine. Bile extract promotes emulsification of fats, increases lipase activity, improves the absorption of fats and fat-soluble vitamins. The enzyme hemicellulase promotes the breakdown of plant fiber. These properties of the drug help to improve the functional state of the gastrointestinal tract, normalize the digestive process.
Pharmacokinetics.
The drug is not absorbed and acts in the lumen of the intestinal tract. The contents of the tablet are protected by an acid-resistant shell, which prevents the inactivation of enzymes (part of the drug) with hydrochloric acid in the stomach. The dissolution of the shell and the release of enzymes occurs in the small intestine, ie in an alkaline environment, which is optimal for the manifestation of enzyme activity.
Enzistal Indication
Replacement therapy for mild to moderate pancreatic exocrine dysfunction in chronic pancreatitis (except in cases of exacerbation of chronic pancreatitis), to improve digestion in ulcerative colitis, irritable bowel syndrome, as well as after gastrectomy; flatulence and some cases of diarrhea of non-infectious origin; to improve the digestion of food for people with normal digestive function in case of eating disorders (eating large amounts of food, eating fatty, fried or unusual foods, irregular meals, etc.); in violation of masticatory function, in conditions that lead to prolonged immobilization; preparation for X-ray and ultrasound examination of the abdominal organs; as an aid for the effective absorption of fat-soluble vitamins and some drugs (PAS, sulfonamides, antibiotics).
Contraindication
Hypersensitivity to the components of the drug, to pancreatic enzymes of animal origin, acute hepatitis, mechanical jaundice, obstructive bowel obstruction, acute pancreatitis, exacerbation of chronic pancreatitis.
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