Description
Epirubicin Amaxa (Epirubicin) Solution for Injections 2 mg/ml. 10 ml Vial №1
Composition
Epirubicin is the active ingredient in Epirubicin Amaxa. Each milliliter of the solution contains 2 mg of epirubicin hydrochloride.
Mechanism of Action
Epirubicin Amaxa, pharmacologically classified as an anthracycline antibiotic, exerts its cytotoxic effects by intercalating DNA strands and inhibiting topoisomerase II. This mechanism leads to DNA damage and ultimately cell death, making it an essential component in the treatment of various cancers.
Pharmacological Properties
Epirubicin Amaxa inhibits DNA and RNA synthesis in cancer cells, disrupting their growth and proliferation. Its mechanism of action contributes to the cytotoxicity against cancer cells, aiding in the treatment of different types of cancers.
Indications for Use
Epirubicin Amaxa is indicated for the treatment of various cancers, including breast cancer, ovarian cancer, and stomach cancer. It interferes with the growth and spread of cancer cells in the body, offering a valuable therapeutic option for patients with these malignancies.
Contraindications
Do not use Epirubicin Amaxa if you have a known allergy to epirubicin or any components of the solution. Prior to initiating treatment, discuss all existing medical conditions and medications with your healthcare provider to prevent adverse reactions.
Side Effects
Common side effects of Epirubicin Amaxa include nausea, vomiting, and hair loss. Monitoring for these adverse effects and discussing management strategies with your healthcare provider is essential during the course of treatment.
Usage Instructions
Epirubicin Amaxa should be administered intravenously by experienced healthcare professionals familiar with chemotherapy drug administration. Follow the specific dosage and infusion rate recommendations provided by your healthcare team for optimal treatment outcomes.
Benefits Compared to Analogues
Comparative studies have demonstrated that Epirubicin Amaxa exhibits comparable efficacy to other anthracycline drugs while potentially offering a more favorable safety profile. Its use in combination therapies has shown promising results in enhancing treatment efficacy and minimizing the development of drug resistance.
Suitable Patient Groups
Epirubicin Amaxa is suitable for use in various patient populations, including adults, the elderly, and pediatric patients under the supervision of healthcare professionals. Individualized dosing considerations may apply based on age, overall health status, and treatment response.
Storage and Shelf Life
Store Epirubicin Amaxa as per the manufacturer’s instructions, typically at controlled room temperature. Check the expiration date on the packaging and do not use the product beyond its stated shelf life to ensure optimal efficacy and safety.
Packaging Description
Epirubicin Amaxa is supplied in a 10 ml vial for injections, providing a convenient and sterile dosage form for healthcare providers to administer the medication safely and accurately.
Clinical Evidence and Proven Effectiveness
Epirubicin, the active ingredient in Epirubicin Amaxa, has undergone extensive clinical evaluation for its efficacy in treating various cancers. Research studies have highlighted its ability to inhibit DNA and RNA synthesis in cancer cells, leading to cell death. Clinical trials have supported the effectiveness of epirubicin in improving survival rates and reducing tumor burden in patients with advanced malignancies.
