Description

Ergos (sildenafil) tablets 50 mg. №8

Ingredients

Active ingredient: Sildenafil citrate
Other ingredients: Microcrystalline cellulose, calcium hydrogen phosphate (anhydrous), croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide (E171), lactose, triacetin, indigo carmine aluminum lake (E132).

Dosage

Recommended dosage: One tablet 30 minutes to 1 hour before sexual activity. Do not exceed one tablet in a 24-hour period.

Indications

Ergos tablets are indicated for the treatment of erectile dysfunction in adult men.

Contraindications

Do not take Ergos tablets if you are allergic to sildenafil or any other ingredients in the product. It is contraindicated to use Ergos with nitrates or nitric oxide donors.

Directions

Take one tablet orally with a glass of water. Avoid high-fat meals before taking Ergos tablets as they may delay the onset of action.

Scientific Evidence

Sildenafil, the active ingredient in Ergos tablets, is a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). By inhibiting PDE5, sildenafil enhances the effects of nitric oxide, leading to smooth muscle relaxation in the corpus cavernosum of the penis and increased blood flow, resulting in an erection. Numerous studies have demonstrated the efficacy of sildenafil in treating erectile dysfunction across various populations.

Additional Information

It is essential to consult a healthcare provider before using Ergos tablets, especially if you have underlying health conditions or are taking other medications. Common side effects may include headache, flushing, indigestion, and nasal congestion. In rare cases, sildenafil may cause serious side effects such as priapism or sudden vision loss. If you experience any severe side effects, seek medical attention immediately.

Pharmacological Effects and Clinical Trials

Sildenafil’s pharmacological action involves the inhibition of PDE5, which results in increased levels of cGMP, leading to vasodilation and improved blood flow to the corpus cavernosum. Clinical trials have shown that sildenafil is effective in achieving and maintaining erections in men with erectile dysfunction of various etiologies. A study published in the Journal of Sexual Medicine demonstrated that sildenafil significantly improved erectile function compared to a placebo, with a high rate of treatment satisfaction among patients.

Overall, Ergos (sildenafil) tablets 50 mg. №8 offer a reliable and well-established treatment option for men experiencing erectile dysfunction. The medication’s mechanism of action, supported by scientific evidence and clinical trials, underscores its efficacy in enhancing sexual performance and quality of life.