Eucabal (acetylcysteine) powder 600 mg. №10

Description

Eucabal №10 Storage
active substance: acetylcysteine;

1 sachet contains acetylcysteine ​​600 mg;

Excipients: sucrose, orange flavor, colloidal anhydrous silica, tartaric acid, sodium chloride.

Eucabal №10 Dosage form
Powder for oral solution.

Main physical and chemical properties: white or almost white homogeneous powder with a fruity odor, does not contain agglomerates and foreign particles.

Pharmacotherapeutic group
Mucolytics.

ATX code R05C B01.

Pharmacological properties

Pharmacodynamics.

Acetylcysteine ​​is a mucolytic, expectorant, which is used to dilute sputum in diseases of the respiratory system, accompanied by the formation of thick mucus.

Acetylcysteine ​​has a pronounced mucolytic effect on mucous and mucopurulent secretions. It reduces the viscosity of mucus and promotes expectoration of bronchial secretions by depolymerizing mucoprotein complexes and nucleic acids, which cause the viscosity of hyaline and purulent components of sputum. Acetylcysteine ​​also has antioxidant and pneumoprotective properties: reduction of induced mucocyte hyperplasia, increase of surfactant production due to stimulation of type II pneumocytes, stimulation of mucociliary apparatus activity, which helps to improve mucociliary clearance.

Acetylcysteine ​​has a direct antioxidant effect due to the presence of a nucleophilic free thiol group (SH). Acetylcysteine ​​prevents the inactivation of α-1-antitrypsin, an enzyme that protects tissues from inflammatory cell enzymes, primarily phagocyte elastase.

In addition, the molecular structure of acetylcysteine ​​allows it to easily penetrate cell membranes. Inside the cell, acetylcysteine ​​is deacetylated to form L-cysteine, an essential amino acid for glutathione synthesis. Acetylcysteine ​​promotes the synthesis of glutathione, which is important for the detoxification of harmful factors. This explains the effect of acetylcysteine ​​as an antidote for paracetamol poisoning.

Eucabal №10 Indication
Treatment of acute and chronic diseases of the bronchopulmonary system, which require reducing the viscosity of sputum, improving its discharge and expectoration.

Contraindication
Hypersensitivity to acetylcysteine or to any of the excipients is known. Gastric and duodenal ulcer in the acute stage, hemoptysis, pulmonary hemorrhage.

Children under 14 years.