$9.00
Manufacturer: Germany
Use for adults and children over 16 yEars and Nose of age. Mild or moderate pain syndrome: headache or toothache, pain with primary dysmenorrhea; migraine, arthralgia, myalgia, neuralgia, especially diseases of inflammatory origin (frontitis, sinusitis), rheumatic diseases, diseases accompanied by hyperthermia of different etiologies (as an antipyretic).
Description
Evro Citramon Storage
active substances: acetylsalicylic acid, paracetamol, caffeine;
1 tablet contains acetylsalicylic acid 250 mg, paracetamol 250 mg, caffeine 50 mg;
excipients: lactose monohydrate; gelatin; corn starch; colloidal anhydrous silica; stearic acid.
Evro Citramon Dosage form
Tablets.
Main physical and chemical properties: flat tablets from white to almost white color with insignificant granularity, with beveled edges and a separate line on one side.
Pharmacotherapeutic group
Analgesics and antipyretics. Acetylsalicylic acid, combinations without psycholeptics.
ATX code N02B A51.
Pharmacological properties
Pharmacodynamics.
Euro Citramon® is a combined drug. Acetylsalicylic acid has antipyretic and anti-inflammatory effects, reduces pain, especially caused by inflammation, as well as inhibits platelet aggregation and thrombosis, improves microcirculation in the inflammatory focus. Paracetamol has analgesic, antipyretic and very weak anti-inflammatory effect, which is due to its effect on the thermoregulatory center in the hypothalamus and a weak ability to inhibit the synthesis of prostaglandins in peripheral tissues.
Caffeine increases the reflex excitability of the spinal cord, stimulates the respiratory and vascular centers, dilates blood vessels of bone muscles, brain, heart, kidneys, reduces platelet aggregation; reduces drowsiness, fatigue, increases mental and physical performance. In this combination, caffeine in small doses has virtually no stimulating effect on the central nervous system, but helps to normalize the tone of blood vessels in the brain and speed up blood flow.
The combination of acetylsalicylic acid and paracetamol potentiates the analgesic effect of the combination in a ratio of 1: 4 to baseline. Both analgesic and antipyretic effects of acetylsalicylic acid and paracetamol are enhanced by the combination of caffeine.
Pharmacokinetics.
Not studied.
Indication
Mild or moderate pain: headache or toothache, pain in primary dysmenorrhea.
Evro Citramon Contraindication
Hypersensitivity to any of the components of the drug; severe hepatic and / or renal impairment; congenital hyperbilirubinemia; glucose-6-phosphate dehydrogenase deficiency; alcoholism, blood diseases, hemophilia, hemorrhagic diathesis, severe anemia, leukopenia, thrombosis, thrombophlebitis; hemorrhagic diseases; acute peptic ulcers; states of heightened arousal, sleep disturbances, epilepsy; pronounced increase in blood pressure; organic diseases of the cardiovascular system (including severe atherosclerosis); glaucoma; hyperthyroidism, decompensated heart failure, cardiac conduction disorders, predisposition to vasospasm, acute myocardial infarction, paroxysmal tachycardia; acute pancreatitis, prostate hypertrophy, severe diabetes mellitus, angle-closure glaucoma, asthma caused by the use of salicylates or nonsteroidal anti-inflammatory drugs (NSAIDs) in the anamnesis; age from 60 years; combination with methotrexate at a dosage of 15 mg / week or more.
Do not use together with monoamine oxidase (MAO) inhibitors and for 2 weeks after discontinuation of MAO inhibitors. Contraindicated in patients taking tricyclic antidepressants or beta-blockers.
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