Description
Evropenem (Meropenem) Powder for Solution for Injections 1g. №10 Vial
Composition
Each vial contains 1g of Meropenem.
Mechanism of Action
Meropenem, a broad-spectrum carbapenem antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins.
Pharmacological Properties
Meropenem demonstrates potent activity against a wide range of bacteria, including both gram-positive and gram-negative organisms. It is stable against many beta-lactamases and exhibits low potential for development of resistance.
Indications for Use
Evropenem is indicated for the treatment of severe infections caused by susceptible strains of bacteria. Common indications include pneumonia, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections.
Contraindications
Evropenem should not be used in individuals with known hypersensitivity to Meropenem or other beta-lactam antibiotics. Caution is advised in patients with a history of seizures or central nervous system disorders.
Side Effects
Common side effects of Evropenem may include diarrhea, nausea, vomiting, headache, and rash. Serious side effects such as allergic reactions and seizures are rare but require immediate medical attention.
Usage Instructions
Evropenem should be reconstituted with the appropriate diluent as directed and administered intravenously by a healthcare professional. The typical dosage regimen involves administering 1g every 8 hours.
Benefits Compared to Analogues
Studies have demonstrated the superior bactericidal activity of Meropenem compared to other antibiotics. Its broad spectrum of activity and low propensity for resistance make it a preferred choice in the treatment of serious infections.
Suitable Patient Groups
Evropenem is suitable for use in both adult and pediatric populations. Dosing adjustments may be necessary in elderly patients or those with renal impairment.
Storage and Shelf Life
Store Evropenem vials at controlled room temperature. Do not freeze. The shelf life of the product is as indicated on the packaging.
Packaging Description
Evropenem is supplied as a powder for solution for injections in vials. Each vial contains 1g of Meropenem and is intended for single-use only.
Clinical Evidence and Proven Effectiveness
Meropenem has been extensively studied and shown to be effective in the treatment of various bacterial infections. Clinical trials have highlighted its efficacy against multi-drug resistant strains and its role as a valuable therapeutic option in serious infections.
