Description
Evroramipril N (Ramipril) 5 Tablets 5 mg/12.5 mg. №20
Ingredients
Each tablet contains: Ramipril 5 mg and Hydrochlorothiazide 12.5 mg.
Mechanism of Action
Ramipril, an ACE inhibitor, works by inhibiting the angiotensin-converting enzyme, leading to vasodilation and reduced aldosterone secretion. Hydrochlorothiazide, a thiazide diuretic, acts on the kidneys to promote diuresis and lower blood pressure.
Pharmacological Properties
Ramipril and Hydrochlorothiazide in Evroramipril N tablets synergistically lower blood pressure by different mechanisms, providing an effective combination for hypertension management.
Indications for Use
Evroramipril N tablets are indicated for:
- Hypertension management
- Reduction of the risk of stroke in patients with hypertension
Contraindications
Avoid use in individuals:
- With a history of angioedema related to previous ACE inhibitor therapy
- With anuria
Side Effects
Common side effects of Evroramipril N may include dizziness, cough, hypotension, and electrolyte imbalances. Contact your healthcare provider if you experience any adverse reactions.
Usage Instructions
Take Evroramipril N tablets:
- Take 1 tablet daily with or without food
- Swallow the tablet whole with a glass of water
Benefits Compared to Analogues
Evroramipril N offers the advantage of combined therapy with an ACE inhibitor and a diuretic in a single tablet, enhancing convenience and compliance compared to separate medications.
Suitable Patient Groups
Evroramipril N is suitable for adult patients, including the elderly, who require dual therapy for hypertension management.
Storage and Shelf Life
Store Evroramipril N tablets in a cool, dry place away from sunlight. Check the expiration date on the packaging and do not use after the specified date.
Packaging Description
Each package of Evroramipril N contains 20 tablets of Ramipril 5 mg and Hydrochlorothiazide 12.5 mg, individually sealed for protection.
Clinical Evidence and Proven Effectiveness
Ramipril: Ramipril has demonstrated significant efficacy in multiple clinical trials for lowering blood pressure and reducing cardiovascular events in hypertensive patients.
Hydrochlorothiazide: Clinical studies have shown that Hydrochlorothiazide, when used in combination with ACE inhibitors like Ramipril, provides enhanced blood pressure control and cardiovascular risk reduction.
Additional Information
Regular monitoring of blood pressure levels is essential during Evroramipril N therapy. Report any side effects or concerns to your healthcare provider promptly. Do not discontinue the medication abruptly without medical advice.
Prior consultation with a healthcare professional is recommended before initiating Evroramipril N treatment, particularly for individuals with kidney disease, diabetes, or liver conditions.