Description

Exemestane Grindex (exemestane) coated tablets 25 mg. №30

Ingredients:

Each coated tablet contains 25 mg of exemestane.

Dosage:

The recommended dose is one 25 mg tablet once daily after a meal.

Indications:

Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen receptor-positive early breast cancer.

Contraindications:

Do not use exemestane if you are pregnant, breastfeeding, or allergic to any of the ingredients.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence:

Exemestane works by inhibiting the enzyme aromatase, which is responsible for converting androgens to estrogens. By reducing estrogen levels in postmenopausal women, exemestane helps prevent the growth of estrogen-sensitive breast cancer cells. Clinical trials have shown that exemestane significantly reduces the risk of cancer recurrence in postmenopausal women with early-stage breast cancer.

Research published in the New England Journal of Medicine demonstrated the efficacy of exemestane in reducing the risk of contralateral breast cancer by 65% compared to a placebo. The study also showed a significant improvement in disease-free survival among patients treated with exemestane.

Additional Information:

• Storage: Store at room temperature away from moisture and heat.
• Side Effects: Common side effects may include hot flashes, headache, fatigue, and joint pain.
• Precautions: Regular monitoring of bone density is recommended during treatment with exemestane.