Fanigan Fast gel 100 g.

Description

Fanigan Fast Composition
active ingredients: 1 g of gel contains diclofenac diethylamine equivalent to diclofenac sodium 10 mg, menthol 50 mg, methyl salicylate 100 mg, linseed oil 30 mg;
excipients: propylene glycol, carbomer 940, sodium edetate, polysorbate 80, benzyl alcohol, ammonia solution, purified water.

Fanigan Fast Dosage form
Gel.
Basic physical and chemical properties: homogeneous white gel with a characteristic odor.

Fanigan Fast Pharmacotherapeutic group
Drugs used topically for joint and muscle pain. Topical non-steroidal anti-inflammatory drugs. Diclofenac.
ATX code M02A A.

Pharmacodynamics
The action of Fanigan® Fast gel is due to the components that make up its composition. Diclofenac is an NSAID with a pronounced anti-inflammatory, analgesic, anti-inflammatory and antipyretic effect. The main mechanism of action is the suppression of the biosynthesis of prostaglandins.

In inflammation caused by injuries or rheumatic diseases, the use of diclofenac leads to a decrease in pain, tissue edema and a reduction in the period of renewal of the functions of damaged joints, ligaments, tendons and muscles.

Menthol irritates the cold receptors. This is accompanied by a narrowing and a decrease in capillary permeability at the site of its application, a feeling of coolness. Menthol produces a local distracting and mild pain relieving effect.

Methyl salicylate is a derivative of salicylic acid and causes local irritation. By irritating the skin receptors, methyl salicylate leads to the creation and release into the blood of a large amount of biologically active substances that regulate pain sensitivity. Substance P is released from neurons. A decrease in the accumulation of substance P in the nerve endings leads to a decrease in pain. In addition, methyl salicylate, which belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs), inhibits the synthesis of prostaglandins due to inhibition of cyclooxygenase, which reduces edema and infiltration of inflamed tissues.

Flaxseed oil, the main component of which is α-linolenic acid (ethyl ester of unsaturated fatty acid), has an anti-inflammatory effect, antioxidant properties, and improves blood circulation at the site of application.

Pharmacokinetics
The action of Fanigan® Fast gel begins within a few minutes after application to the skin.

After 20-30 minutes, the effect of the gel reaches its maximum. The disappearance of the main clinical symptoms is usually noted within the first days after the start of treatment.

When the gel is applied topically, less than 5% of the dose is absorbed, thus the systemic effect of the drug is minimal.

Indications
Local treatment of myositis, fibrositis, sciatica, stretching of muscles and tendons, traumatic injuries of the musculoskeletal system, pain in muscles and joints during severe physical exertion, inflammatory and degenerative diseases of the joints (ostearthritis of the peripheral joints and spine), rheumatic lesions of the musculoskeletal system (bursitis , arthritis, tendosynovitis, tendonitis).

Contraindications
Hypersensitivity to diclofenac or other components of the drug;
a history of attacks of bronchial asthma, urticaria or acute rhinitis caused by the intake of acetylsalicylic acid or other NSAIDs. Damage to the epidermis, open wounds in the area of ​​application;
the last trimester of pregnancy.
Interaction with other medicinal products and other types of interactions
Since systemic absorption following topical application of the drug is very low, the likelihood of interactions is very low. However, one must consider possible interactions that are known for oral forms of diclofenac.

Application features
Use with caution in conjunction with oral NSAIDs. The likelihood of developing systemic side effects with topical application of diclofenac is insignificant compared with the use of its oral forms, but it is not excluded when the drug is used on relatively large areas of the skin for a long time.

Fanigan® Fast gel should not be used with other products containing diclofenac. The drug should be used with caution in case of peptic ulcer of the stomach and duodenum in the acute stage and its presence in history, impaired liver / kidney function, hematopoiesis disorder, polyposis of the nasal mucosa.
Fanigan® Fast gel is recommended to be applied only to intact skin areas, avoiding contact with inflamed, wounded or infected skin. Avoid contact of the drug with the eyes and mucous membranes. The drug should not be swallowed.